PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
Database | Last Updated |
---|---|
Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
---|---|---|---|---|---|---|---|
VP8 (spike protein)
|
Sialic acid
|
Monosaccharides
|
Binding
|
||||
Unknown
|
unnamed ligand
|
Disaccharides
|
GalNAc(b1-3)Gal
|
Binding
|
|||
HIV surface glycoprotein gp120
|
Galactosylceramide (Galactocerebroside)
|
Monoglycosylceramides
|
Neural cell lines
|
Gal(b1-1)Cer
|
Binding
|
||
MuV-HN
|
Glycans containing α2,6-linked sialic acid
|
Oligosaccharides
|
NeuAc(a2-6)Gal(b1-4)GlcNAc
|
Not Binding
|
|||
MuV-HN
|
Glycans containing α2,3-linked sialic acid
|
Oligosaccharides
|
NeuAc(a2-3)Gal(b1-4)GlcNAc
|
Binding
|
|||
Adhesins
|
Asialo-GM2 (Gangliotriosylceramide; GgO3)
|
Oligoglycosylceramides
|
Type-II lung cells, Vascular endothelial cells
|
GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
||
Unknown
|
unnamed ligand
|
Sialoglycosphingolipids
|
Bovine buttermilk
|
Gal(b1-4)GlcNAc(b1-6)[NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-3)]Gal(b1-4)Glc(b1-1)Cer
|
Not Binding
|
||
PO
|
unnamed ligand
|
Oligosaccharides
|
human erythrocytes
|
Gal(a1-4)Gal
|
Binding
|
||
A27L proteins
|
Heparan sulfate
|
Glycosaminoglycans
|
Mammalian cell surface
|
Binding
|
|||
Unknown
|
Asialo-GM2 (Gangliotriosylceramide; GgO3)
|
Oligoglycosylceramides
|
GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.
Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01