GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name	Ligand Feature	Target Source	Glycan Sequence	Binding ▲	PubMed ID
Clostridium difficile	Toxin A	α-Gal on Fab of IgM(λ) MAb	Glycoproteins	Mouse	Gal	Binding	9573079
Norovirus	Unknown	Blood group B antigen (B-tri-HSA)	Glycoproteins	Human serum albumin	Gal(a1-3)[Fuc(a1-2)]Gal(b)-O-APE	Binding	19054801
Norovirus	Unknown	Blood group A antigen (A-tri-HSA)	Glycoproteins	Human serum albumin	GalNAc(a1-3)[Fuc(a1-2)]Gal(b)-O-APE	Binding	19054801
Norovirus	Unknown	Blood group A antigen (A-tri-HSA)	Glycoproteins	Saliva	GalNAc(a1-3)[Fuc(a1-2)]Gal(b)-O-APE	Binding	18701592
Clostridium difficile	Unknown	α-Gal on Fab of IgA(κ) MAb	Glycoproteins	Mouse	Gal	Binding	9573079
Clostridium difficile	Unknown	α-Gal on Fab of IgM(λ) MAb	Glycoproteins	Mouse	Gal	Binding	9573079
Human immunodeficiency virus	gp120	Galactosylceramide (Galactocerebroside)	Monoglycosylceramides	Human colonic epithelial cell lines (HT-29/HT-29-A7/HT-29-D4)	Gal(b1-1)Cer	Binding	8464878
Burkholderia cepacia	Lectin-like proteins (adhesin)	Galactosylceramide (Galactocerebroside)	Monoglycosylceramides	Sputa of cystic fibrosis patients	Gal(b1-1)Cer	Binding	8606110
Escherichia coli	S-fimbriae (SfaA)	Galactosylceramide (Galactocerebroside)	Monoglycosylceramides	Brain endothelial cells	Gal(b1-1)Cer	Binding	8098039
Human immunodeficiency virus	HIV surface glycoprotein gp120	Galactosylceramide (Galactocerebroside)	Monoglycosylceramides	Neural cell lines	Gal(b1-1)Cer	Binding	1857969