PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
Database | Last Updated |
---|---|
Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
---|---|---|---|---|---|---|---|
F1C
|
Gb2 (Galabiosylceramide)
|
Diosylceramides
|
Synthetic
|
Gal(a1-4)Gal(b1-1)Cer
|
Not Binding
|
||
Unknown
|
Salivary glycoprotein
|
Glycoproteins
|
Human saliva
|
Binding
|
|||
P-fimbriae
|
GL-II glycolipid
|
Glycolipids
|
Not Binding
|
||||
Unknown
|
GM4
|
Monosialoglycosphingolipids
|
NeuAc(a2-3)Gal(b1-1)Cer
|
Not Binding
|
|||
FHA (filamentous hemagglutinin)
|
Heparan sulfate
|
Glycosaminoglycans
|
Binding
|
||||
Unknown
|
Fucosyl Asialo GM1
|
Oligoglycosylceramides
|
Fuc(a1-2)Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
|||
PapG (class II)
|
DSGG (Disialosyl galactosyl globoside, disialyl Gb5)
|
Disialoglycosphingolipids
|
Human kidney tissues
|
NeuAc(a2-3)Gal(b1-3)[NeuAc(a2-6)]GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
||
A27L proteins
|
Heparan sulfate
|
Glycosaminoglycans
|
Mammalian cell surface
|
Binding
|
|||
Adhesins
|
Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1)
|
Oligoglycosylceramides
|
Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
|||
K88ab/K88ac/K88ad
|
Lewis x (Lex) (GSL)
|
Oligoglycosylceramides
|
Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer
|
Not Binding
|
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Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01