PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
Database | Last Updated |
---|---|
Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding ▲ | PubMed ID |
---|---|---|---|---|---|---|---|
F1C
|
Galactosylceramide (t18:0-h22:0-h24:0)
|
Monoglycosylceramides
|
Human kidney
|
Gal(b1-1)Cer
|
Binding
|
||
gp120
|
Galactosylceramide (Galactocerebroside)
|
Monoglycosylceramides
|
Human U373-MG glioma and SK-N-MC neuroblastoma cells, Human colon epithelial HT29 cells
|
Gal(b1-1)Cer
|
Binding
|
||
Envelope glycoprotein gp120
|
Galactosylceramide (Galactocerebroside)
|
Monoglycosylceramides
|
Neural receptor
|
Gal(b1-1)Cer
|
Binding
|
||
SBA (soybean agglutinin)
|
N-Acetylgalactosamine
|
Monosaccharides
|
Vero E6/P388D1 cells
|
GalNAc
|
Binding
|
||
Type-2 fimbrial lectins (130-kDa glycoprotein)
|
N-Acetylgalactosamine
|
Monosaccharides
|
Polymorphonuclear leukocytes (PMNs)
|
GalNAc
|
Binding
|
||
Type-2 fimbrial lectins (130-kDa glycoprotein)
|
Galactose
|
Monosaccharides
|
Polymorphonuclear leukocytes (PMNs)
|
Gal
|
Binding
|
||
Transmembrane heavy subunit (Hgl; 170-kDa) disulfide linked to a GPI-anchored light subunit (Lgl; 31-to 35-kDa).
|
N-Acetylgalactosamine
|
Monosaccharides
|
Intestinal cells
|
GalNAc
|
Binding
|
||
Transmembrane heavy subunit (Hgl; 170-kDa) disulfide linked to a GPI-anchored light subunit (Lgl; 31-to 35-kDa).
|
Galactose
|
Monosaccharides
|
Intestinal cells
|
Gal
|
Binding
|
||
Gal/GalNAc Lectins (260-kDa)
|
N-Acetylgalactosamine
|
Monosaccharides
|
c-Met on hepatocytes
|
GalNAc
|
Binding
|
||
Gal/GalNAc Lectins (260-kDa)
|
Galactose
|
Monosaccharides
|
c-Met on hepatocytes
|
Gal
|
Binding
|
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Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01