Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB) June 1, 2016
Species Pathogen Adherence Molecule Ligand Name Ligand Feature Target Source Glycan Sequence Binding ▲ PubMed ID
F1C
Galactosylceramide (t18:0-h22:0-h24:0)
Monoglycosylceramides
Human kidney
Gal(b1-1)Cer
Binding
gp120
Galactosylceramide (Galactocerebroside)
Monoglycosylceramides
Human U373-MG glioma and SK-N-MC neuroblastoma cells, Human colon epithelial HT29 cells
Gal(b1-1)Cer
Binding
Envelope glycoprotein gp120
Galactosylceramide (Galactocerebroside)
Monoglycosylceramides
Neural receptor
Gal(b1-1)Cer
Binding
SBA (soybean agglutinin)
N-Acetylgalactosamine
Monosaccharides
Vero E6/P388D1 cells
GalNAc
Binding
Type-2 fimbrial lectins (130-kDa glycoprotein)
N-Acetylgalactosamine
Monosaccharides
Polymorphonuclear leukocytes (PMNs)
GalNAc
Binding
Type-2 fimbrial lectins (130-kDa glycoprotein)
Galactose
Monosaccharides
Polymorphonuclear leukocytes (PMNs)
Gal
Binding
Transmembrane heavy subunit (Hgl; 170-kDa) disulfide linked to a GPI-anchored light subunit (Lgl; 31-to 35-kDa).
N-Acetylgalactosamine
Monosaccharides
Intestinal cells
GalNAc
Binding
Transmembrane heavy subunit (Hgl; 170-kDa) disulfide linked to a GPI-anchored light subunit (Lgl; 31-to 35-kDa).
Galactose
Monosaccharides
Intestinal cells
Gal
Binding
Gal/GalNAc Lectins (260-kDa)
N-Acetylgalactosamine
Monosaccharides
c-Met on hepatocytes
GalNAc
Binding
Gal/GalNAc Lectins (260-kDa)
Galactose
Monosaccharides
c-Met on hepatocytes
Gal
Binding
Displaying entries 71 - 80 of 1840 in total

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01