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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule ▲ | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Escherichia coli | F1C | Disialosyl lacto-N-nor-hexaosylceramide (DSnHC) | Sialoglycosphingolipids | NeuAc(a2-8)NeuAc(a2-3)[Gal(b1-4)GlcNAc]2(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 10816509 | |
| Escherichia coli | F1C | Gb2 (Galabiosylceramide) | Diosylceramides | Synthetic | Gal(a1-4)Gal(b1-1)Cer | Not Binding | 11877427 |
| Escherichia coli | F1C | Lewis a (Lea) (GSL) | Glycosphingolipids | Human meconium | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11877427 |
| Escherichia coli | F1C | Gb5 (Forssman glycolipid) | Oligoglycosylceramides | Dog intestine | GalNAc(a1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11877427 |
| Escherichia coli | F1C | isoGb4 (Isoglobotetraosylceramide; iGb4) | Oligoglycosylceramides | Rat intestine | GalNAc(b1-3)Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11877427 |
| Escherichia coli | F1C | H5 type 1 pentaglycosylceramide (lacto-series) | Oligoglycosylceramides | Human small intestine | Fuc(a1-2)Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11877427 |
| Escherichia coli | F1C | Alpha-Galactosyl paragloboside | Oligoglycosylceramides | Rabbit erythrocytes | Gal(a1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11877427 |
| Escherichia coli | F1C | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) (d18:1-16:0/24:0) | Oligoglycosylceramides | Human erythrocytes | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11877427 |
| Escherichia coli | F1C | Lewis x (Lex) (GSL) | Oligoglycosylceramides | Dog intestine | Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11877427 |
| Escherichia coli | F1C | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Mouse feces | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11877427 |
| Escherichia coli | F1C | Gb2 (Galabiosylceramide) | Diosylceramides | Gal(a1-4)Gal(b1-1)Cer | Not Binding | 10816509 | |
| Escherichia coli | F1C | Ceramide | Non-glycosylated Lipids | Cer | Not Binding | 10816509 | |
| Escherichia coli | F1C | Gb5 (Forssman glycolipid) | Oligoglycosylceramides | GalNAc(a1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 10816509 | |
| Bordetella pertussis | FHA (1141-1279) | Lactosylceramide (Lactocerebroside) | Diosylceramides | Ciliated epithelium of the respiratory tract | Gal(b1-4)Glc(b1-1)Cer | Binding | 11348687 |
| Bordetella pertussis | FHA (442-863) | Heparin | Glycosaminoglycans | WiDr cells, HeLa cells, Vero cells, Extracellular matrix (ECM) | Binding | 11348687 | |
| Bordetella pertussis | FHA (442-863) | Heparin | Glycosaminoglycans | Respiratory epithelial cells | Binding | 17106803 | |
| Bordetella pertussis | FHA (442-863) | Dextran sulfate | Polysaccharides | WiDr cells, HeLa cells, Vero cells, Extracellular matrix (ECM) | Binding | 11348687 | |
| Bordetella pertussis | FHA (filamentous hemagglutinin) | Sulfatide (CSE) | Sulfoglycosphingolipids | Cell surface | HSO3(-3)Gal(b1-1)Cer | Binding | 10341176 |
| Bordetella pertussis | FHA (filamentous hemagglutinin) | Sulfatide (CSE) | Sulfoglycosphingolipids | HSO3(-3)Gal(b1-1)Cer | Binding | 8574698 | |
| Bordetella pertussis | FHA (filamentous hemagglutinin) | Heparan sulfate | Glycosaminoglycans | Binding | 8574698 | ||
| Bordetella pertussis | FHA (filamentous hemagglutinin) | Heparan sulfate | Glycosaminoglycans | Binding | 8574698 | ||
| Bordetella pertussis | FHA (filamentous hemagglutinin) | Heparan sulfate | Glycosaminoglycans | Binding | 8574698 | ||
| Bordetella pertussis | FHA (filamentous hemagglutinin) | Heparan sulfate | Glycosaminoglycans | Binding | 8574698 | ||
| Bordetella pertussis | FHA (filamentous hemagglutinin) | Galactose on sulfated glycolipids | Glycolipids | Gal | Binding | 12640357 | |
| Bordetella pertussis | FHA (tail region) | Complement receptor 3 (CR3) integrins | Glycoproteins | Macrophages | Binding | 11348687 |
