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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature ▲ | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Clostridium difficile | Unknown | β-Gal on Fab of IgG3(λ) MAb | Glycoproteins | Mouse | Gal | Binding | 9573079 |
| Equine rhinitis A virus | Viral protein | α-mannose and α-glucose side chains of ConA-binding glycoproteins | Glycoproteins | Feline kidney(CRFK)/Equine fetal kidney(EFK)/Mouse(McCoy)/Rabbit kidney(RK-13) | Man/Glc | Binding | 15302947 |
| Streptococcus gordonii | Ca2+-independent lectins | Hs antigen | Glycoproteins | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc-HSA | Binding | 9393794 | |
| Norovirus | Unknown | Blood group B antigen (B-tri-HSA) | Glycoproteins | Gal(a1-3)[Fuc(a1-2)]Gal(b)-O-APE | Not Binding | 18701592 | |
| Helicobacter pylori | BabA (blood group antigen binding adhesin) | Blood group H1 antigen (HSA) | Glycoproteins | Fuc(a1-2)Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(c)-APD | Binding | 15273394 | |
| Streptococcus suis | Unknown | Neoglycoproteins (containing P1 Antigen) | Glycoproteins | Gal(a1-4)Gal(b1-4)GlcNAc | Binding | 8440715 | |
| Adenovirus | Fibre proteins | HSA glycoconjugates | Glycoproteins | Human corneal epithelial(HEC) cells | Binding | 15678425 | |
| Entamoeba histolytica | Transmembrane heavy subunit (Hgl; 170-kDa) disulfide linked to a GPI-anchored light subunit (Lgl; 31-to 35-kDa). | β-2 and β-7 integrins | Glycoproteins | Intestinal cells | Binding | 15322032 | |
| Sporothrix schenckii | Yeast cells and conidia | Fibronectin | Glycoproteins | Extracellular matrix (ECM) | Binding | 11598061 | |
| Paracoccidioides brasiliensis | Adhesins | Fibronectin | Glycoproteins | Human type II alveolar cells (A549) | Binding | 18083324 | |
| Paracoccidioides brasiliensis | Adhesins | Fibrinogen | Glycoproteins | Human type II alveolar cells (A549) | Binding | 18083324 | |
| Streptococcus pyogenes | Protein F (Antigen I/II) | Fibronectin | Glycoproteins | Respiratory endothelial cells | Binding | 10341176 | |
| Streptococcus pyogenes | Protein F (Antigen I/II) | Fibronectin | Glycoproteins | Respiratory epithelial cells | Binding | 1385871 | |
| Neisseria meningitidis | Type 4-pili | Agglutinin glycoproteins containing O-/N-linked (poly)lactosamine and hybrid oligosaccharides | Glycoproteins | Human saliva | Binding | 16177210 | |
| Leptospira interrogans | Lsa24 | Laminin | Glycoproteins | Extracellular matrix (ECM) | Binding | 16954400 | |
| Coronavirus | Unknown | MHVR (murine member of the carcinoembryonic antigen family of glycoproteins) | Glycoproteins | BHK-21 cells | Binding | 1318394 | |
| Streptococcus pyogenes | Sfbl (Antigen I/II) | Fibronectin | Glycoproteins | Respiratory endothelial cells | Binding | 10341176 | |
| Mycoplasma pneumoniae | Adhesins | Laminin | Glycoproteins | Murine Engelbreth Holm Swarm tumor, Murine erythrocytes | Binding | 2470754 | |
| Mycoplasma pneumoniae | Adhesins | hCG (human chorionic gonadotropin) | Glycoproteins | Erythrocytes | Binding | 2470754 | |
| Streptococcus pyogenes | Sfbl (Antigen I/II) | Fibronectin | Glycoproteins | Respiratory epithelial cells | Binding | 12640357 | |
| Sporothrix schenckii | Yeast cells and hyphae | Fibronectin | Glycoproteins | Extracellular matrix (ECM) | Binding | 15351036 | |
| Sporothrix schenckii | Yeast cells and hyphae | Laminin | Glycoproteins | Extracellular matrix (ECM) | Binding | 15351036 | |
| Streptococcus pyogenes | Protein F (Antigen I/II) | Fibronectin | Glycoproteins | Respiratory epithelial cells | Binding | 12640357 | |
| Bordetella pertussis | FimD | VLA-5 (very late activation antigen 5) | Glycoproteins | Monocytes | Binding | 11348687 | |
| Influenza virus | Unknown | Glycoproteins | Glycoproteins | Rat serum | Binding | 1740131 |
