Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature ▲ | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Streptococcus pyogenes | Protein F (Antigen I/II) | Fibronectin | Glycoproteins | Respiratory epithelial cells | Binding | 1385871 | |
| Leptospira interrogans | Lsa24 | Laminin | Glycoproteins | Extracellular matrix (ECM) | Binding | 16954400 | |
| Coronavirus | Unknown | MHVR (murine member of the carcinoembryonic antigen family of glycoproteins) | Glycoproteins | BHK-21 cells | Binding | 1318394 | |
| Streptococcus pyogenes | Sfbl (Antigen I/II) | Fibronectin | Glycoproteins | Respiratory endothelial cells | Binding | 10341176 | |
| Mycoplasma pneumoniae | Adhesins | Laminin | Glycoproteins | Murine Engelbreth Holm Swarm tumor, Murine erythrocytes | Binding | 2470754 | |
| Streptococcus pyogenes | Sfbl (Antigen I/II) | Fibronectin | Glycoproteins | Respiratory epithelial cells | Binding | 12640357 | |
| Sporothrix schenckii | Yeast cells and hyphae | Fibronectin | Glycoproteins | Extracellular matrix (ECM) | Binding | 15351036 | |
| Sporothrix schenckii | Yeast cells and hyphae | Laminin | Glycoproteins | Extracellular matrix (ECM) | Binding | 15351036 | |
| Streptococcus pyogenes | Protein F (Antigen I/II) | Fibronectin | Glycoproteins | Respiratory epithelial cells | Binding | 12640357 | |
| Influenza virus | Unknown | Alpha-1-acid glycoprotein (AGP) | Glycoproteins | Human | Not Binding | 1740131 | |
| Influenza virus | Unknown | Glycoproteins | Glycoproteins | Rat serum | Binding | 1740131 | |
| Influenza virus | Unknown | Glycoproteins | Glycoproteins | Guinea pig serum | Not Binding | 1740131 | |
| Entamoeba histolytica | Raft-like plasma membrane domains | β-2 and β-7 integrins | Glycoproteins | Intestinal cells | Binding | 15322032 | |
| Streptococcus gordonii | Ca2+-independent lectins | Hs antigen | Glycoproteins | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc-HSA | Binding | 9393794 | |
| Norovirus | Unknown | Blood group A antigen (A-tri-HSA) | Glycoproteins | GalNAc(a1-3)[Fuc(a1-2)]Gal(b)-O-APE | Not Binding | 18701592 | |
| Norovirus | Unknown | Blood group B antigen (B-tri-HSA) | Glycoproteins | Gal(a1-3)[Fuc(a1-2)]Gal(b)-O-APE | Not Binding | 18701592 | |
| Helicobacter pylori | BabA (blood group antigen binding adhesin) | Blood group H1 antigen (HSA) | Glycoproteins | Fuc(a1-2)Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(c)-APD | Binding | 15273394 | |
| Streptococcus suis | Unknown | Neoglycoproteins (containing P1 Antigen) | Glycoproteins | Gal(a1-4)Gal(b1-4)GlcNAc | Binding | 8440715 | |
| Paracoccidioides brasiliensis | Paracoccin | Laminin | Glycoproteins | Binding | 16476564 | ||
| Staphylococcus aureus | FnbA | Fibronectin | Glycoproteins | Binding | 10341176 | ||
| Streptococcus gordonii | CshB | Fibronectin | Glycoproteins | Binding | 10341176 | ||
| Escherichia coli | FimH | Tamm-Horsfall protein (THP) | Glycoproteins | Binding | 12010488 | ||
| Escherichia coli | FimH | Fibronectin | Glycoproteins | Binding | 12010488 | ||
| Escherichia coli | FimH | Laminin | Glycoproteins | Binding | 12010488 | ||
| Streptococcus gordonii | CshaB (Antigen I/II) | Fibronectin | Glycoproteins | Binding | 12640357 |
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