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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature ▲ | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Helicobacter mustelae | Lectin-hemagglutinin adhesins | Acid glycosphingolipids | Acidic Glycosphingolipids | Human granulocytes | Binding | 12704182 | |
| Helicobacter pylori | Lectin-hemagglutinin adhesins | Acid glycosphingolipids | Acidic Glycosphingolipids | Human granulocytes | Binding | 12704182 | |
| Helicobacter hepaticus | Lectin-hemagglutinin adhesins | Acid glycosphingolipids | Acidic Glycosphingolipids | Human granulocytes | Binding | 12704182 | |
| Helicobacter pylori | HPNAP (neutrophil-activating protein of H. pylori) | Acid glycosphingolipids | Acidic Glycosphingolipids | Human neutrophil granulocytes | Binding | 11087709 | |
| Helicobacter bilis | Lectin-hemagglutinin adhesins | Acid glycosphingolipids | Acidic Glycosphingolipids | human granulocytes | Not Binding | 12704182 | |
| Helicobacter mustelae | Lectin-hemagglutinin adhesins | Acid glycosphingolipids | Acidic Glycosphingolipids | human granulocytes | Not Binding | 12704182 | |
| Helicobacter felis | Lectin-hemagglutinin adhesins | Acid glycosphingolipids | Acidic Glycosphingolipids | human granulocytes | Not Binding | 12704182 | |
| Helicobacter canis | Lectin-hemagglutinin adhesins | Acid glycosphingolipids | Acidic Glycosphingolipids | human granulocytes | Not Binding | 12704182 | |
| Helicobacter pylori | Lectin-hemagglutinin adhesins | Acid glycosphingolipids | Acidic Glycosphingolipids | Not Binding | 12704182 | ||
| Escherichia coli | F1C | Lactosylceramide (t18:0-h16:0-h24:0) | Diosylceramides | Rabbit small intestine | Gal(b1-4)Glc(b1-1)Cer | Binding | 11877427 |
| Rotavirus | Unknown | Lactosylceramide (t18:0-h16:0-h24:0) | Diosylceramides | Gal(b1-4)Glc(b1-1)Cer | Binding | 11160731 | |
| Burkholderia cepacia | Lectin-like proteins (adhesin) | Gb2 (Galabiosylceramide) | Diosylceramides | Sputa of cystic fibrosis patients | Gal(a1-4)Gal(b1-1)Cer | Binding | 8606110 |
| Escherichia coli | P-fimbriae | Gb2 (Galabiosylceramide) | Diosylceramides | Urine | Gal(a1-4)Gal(b1-1)Cer | Binding | 16564136 |
| Escherichia coli | P-pili | Gb2 (Galabiosylceramide) | Diosylceramides | Epithelial cells in human urinary tract | Gal(a1-4)Gal(b1-1)Cer | Binding | 9007266 |
| Helicobacter pylori | 35S-labeled or 125I-labeled proteins | Lactosylceramide (d18:1-16:0/24:1) | Diosylceramides | Human granulocytes, Human erythrocytes | Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9499377 |
| Helicobacter pylori | 35S-labeled or 125I-labeled proteins | Lactosylceramide (d18:1-h16:0/t18:0-h24:0/t18:0-h16:0) | Diosylceramides | Dog small intestine | Gal(b1-4)Glc(b1-1)Cer | Binding | 9499377 |
| Escherichia coli | F1C | Lactosylceramide (d18:1-16:0/24:1) | Diosylceramides | Human neutrophils | Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11877427 |
| Escherichia coli | F1C | Gb2 (Galabiosylceramide) | Diosylceramides | Synthetic | Gal(a1-4)Gal(b1-1)Cer | Not Binding | 11877427 |
| Neisseria gonorrhoeae | Lectin-like proteins (adhesin) | Gb2 (Galabiosylceramide) | Diosylceramides | Gonorrhoeae patients | Gal(a1-4)Gal(b1-1)Cer | Not Binding | 2468365 |
| Escherichia coli | PapG (class II) | Gb2 (Galabiosylceramide) | Diosylceramides | Epithelial cells in human urinary tract | Gal(a1-4)Gal(b1-1)Cer | Binding | 9007266 |
| Actinomyces viscosus | Unknown | Gb2 (Galabiosylceramide) | Diosylceramides | Human meconium | Gal(a1-4)Gal(b1-1)Cer | Not Binding | 2358461 |
| Shigella dysenteriae | B subunit | Gb2 (Galabiosylceramide) | Diosylceramides | Human meconium | Gal(a1-4)Gal(b1-1)Cer | Binding | 3543013 |
| Actinomyces naeslundii | Unknown | Gb2 (Galabiosylceramide) | Diosylceramides | Human meconium | Gal(a1-4)Gal(b1-1)Cer | Not Binding | 2358461 |
| Streptococcus suis | Adhesins | Gb2 (Galabiosylceramide) | Diosylceramides | Gal(a1-4)Gal(b1-1)Cer | Binding | 7961660 | |
| Escherichia coli | P-fimbriae | Gb2 (Galabiosylceramide) | Diosylceramides | Gal(a1-4)Gal(b1-1)Cer | Binding | 7721812 |
