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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name ▲ | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Paramyxovirus | Unknown | 116 kDa glycoprotein (containing sialic acid residues with N-linked glycans) | N-glycans | Neurones of all brain regions | Binding | 11666031 | |
| Actinomyces viscosus | Unknown | A6 type 2 glycosphingolipid (A6-2) | Oligoglycosylceramides | Dog small intestine | GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Lactobacillus johnsonii | Unknown | A6 type 2 glycosphingolipid (A6-2) | Oligoglycosylceramides | Human erythrocytes | GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11087711 |
| Shigella dysenteriae | B subunit | A6 type 2 glycosphingolipid (A6-2) | Oligoglycosylceramides | Dog small intestine | GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 3543013 |
| Actinomyces naeslundii | Unknown | A6 type 2 glycosphingolipid (A6-2) | Oligoglycosylceramides | Dog small intestine | GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Helicobacter mustelae | Lectin-hemagglutinin adhesins | Acid glycosphingolipids | Acidic Glycosphingolipids | Human granulocytes | Binding | 12704182 | |
| Helicobacter pylori | Lectin-hemagglutinin adhesins | Acid glycosphingolipids | Acidic Glycosphingolipids | Human granulocytes | Binding | 12704182 | |
| Helicobacter hepaticus | Lectin-hemagglutinin adhesins | Acid glycosphingolipids | Acidic Glycosphingolipids | Human granulocytes | Binding | 12704182 | |
| Helicobacter pylori | HPNAP (neutrophil-activating protein of H. pylori) | Acid glycosphingolipids | Acidic Glycosphingolipids | Human neutrophil granulocytes | Binding | 11087709 | |
| Helicobacter mustelae | Lectin-hemagglutinin adhesins | Acid glycosphingolipids | Acidic Glycosphingolipids | human granulocytes | Not Binding | 12704182 | |
| Helicobacter canis | Lectin-hemagglutinin adhesins | Acid glycosphingolipids | Acidic Glycosphingolipids | human granulocytes | Not Binding | 12704182 | |
| Helicobacter bilis | Lectin-hemagglutinin adhesins | Acid glycosphingolipids | Acidic Glycosphingolipids | human granulocytes | Not Binding | 12704182 | |
| Helicobacter felis | Lectin-hemagglutinin adhesins | Acid glycosphingolipids | Acidic Glycosphingolipids | human granulocytes | Not Binding | 12704182 | |
| Helicobacter pylori | Lectin-hemagglutinin adhesins | Acid glycosphingolipids | Acidic Glycosphingolipids | Not Binding | 12704182 | ||
| Neisseria meningitidis | Type 4-pili | Agglutinin glycoproteins containing O-/N-linked (poly)lactosamine and hybrid oligosaccharides | Glycoproteins | Human saliva | Binding | 16177210 | |
| Influenza virus | Unknown | Alpha-1-acid glycoprotein (AGP) | Glycoproteins | Human | Not Binding | 1740131 | |
| Mycoplasma pneumoniae | Unknown | Alpha-Galactosyl paragloboside | Oligoglycosylceramides | Human colon adenocarcinoma cells (WiDr ) | Gal(a1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2470753 |
| Escherichia coli | F1C | Alpha-Galactosyl paragloboside | Oligoglycosylceramides | Rabbit erythrocytes | Gal(a1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11877427 |
| Lactobacillus johnsonii | Unknown | Alpha-Galactosyl paragloboside | Oligoglycosylceramides | Rabbit erythrocytes | Gal(a1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11087711 |
| Shigella dysenteriae | B subunit | Alpha-Galactosyl paragloboside | Oligoglycosylceramides | Rabbit erythrocytes | Gal(a1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 3543013 |
| Rotavirus | Unknown | Alpha-Galactosyl paragloboside | Oligoglycosylceramides | Gal(a1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11160731 | |
| Pseudomonas aeruginosa | LecA | Alpha-methyl-galactoside | Monosaccharides | A549 cells | Binding | 19237519 | |
| Bordetella pertussis | Adhesins | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Human lung, Human trachea | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 1918002 |
| Burkholderia cepacia | Lectin-like proteins (adhesin) | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Sputa of cystic fibrosis patients | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 8606110 |
| Streptococcus pneumoniae | Adhesins | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Type-II lung cells, Vascular endothelial cells | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 7752878 |
