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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule ▲ | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Moraxella catarrhalis | Fimbriae | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Human pharyngeal epithelial cells | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 12137200 |
| Neisseria gonorrhoeae | Fimbriae | Lactosylceramide (Lactocerebroside) | Diosylceramides | Gal(b1-4)Glc(b1-1)Cer | Binding | 10816509 | |
| Neisseria gonorrhoeae | Fimbriae | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 10816509 | |
| Neisseria gonorrhoeae | Fimbriae | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 10816509 | |
| Pseudomonas aeruginosa | Fimbriae | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 10816509 | |
| Escherichia coli | Fimbrial lectin (adhesin) protein GafD (25-kDa) | N-Acetylglucosamine | Monosaccharides | GlcNAc | Binding | 7883703 | |
| Pseudomonas aeruginosa | Flagellin | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Epithelial cells | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9224879 |
| Pseudomonas aeruginosa | Flagellin | MUC1 mucin | Glycoproteins | Epithelial cells | Binding | 11880301 | |
| Pseudomonas aeruginosa | Flagellin | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Epithelial cells | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9224879 |
| Staphylococcus aureus | FnBPA (fibronectin binding protein) | Fibronectin | Glycoproteins | Binding | 1837266 | ||
| Staphylococcus aureus | FnBPB (fibronectin binding protein) | Fibronectin | Glycoproteins | Binding | 1837266 | ||
| Staphylococcus aureus | FnbA | Fibronectin | Glycoproteins | Binding | 10341176 | ||
| Staphylococcus aureus | FnbA | Fibronectin | Glycoproteins | Binding | 12640357 | ||
| Staphylococcus aureus | FnbB | Fibronectin | Glycoproteins | Binding | 12640357 | ||
| Staphylococcus aureus | FnbB | Fibronectin | Glycoproteins | Binding | 10341176 | ||
| Entamoeba histolytica | Gal/GalNAc Lectins (260-kDa) | N-Acetylgalactosamine | Monosaccharides | c-Met on hepatocytes | GalNAc | Binding | 9878032 |
| Entamoeba histolytica | Gal/GalNAc Lectins (260-kDa) | Galactose | Monosaccharides | c-Met on hepatocytes | Gal | Binding | 9878032 |
| Lassa virus | Glycoprotein (GP) | O-mannosyl glycans on alpha-dystroglycan (DG) | O-glycans | Fibroblasts, Epithelial cells, Endothelial cells, Hepatocytes | Binding | 17360738 | |
| Lymphocytic choriomeningitis virus | Glycoprotein (GP) | O-mannosyl glycans on alpha-dystroglycan (DG) | O-glycans | Fibroblasts, Epithelial cells, Endothelial cells, Hepatocytes | Binding | 17360738 | |
| New world arenavirus | Glycoprotein (GP) | O-mannosyl glycans on alpha-dystroglycan (DG) | O-glycans | Binding | 17360738 | ||
| Clostridium botulinum | HA | Lactose | Disaccharides | Intestinal epithelial cells (T84) | Gal(b1-4)Glc | Binding | 17156748 |
| Clostridium botulinum | HA | N-Acetylgalactosamine | Monosaccharides | Intestinal epithelial cells (T84) | GalNAc | Binding | 17156748 |
| Clostridium botulinum | HA | Galactose | Monosaccharides | Intestinal epithelial cells (T84) | Gal | Binding | 17156748 |
| Clostridium botulinum | HA | N-Acetylglucosamine | Monosaccharides | Intestinal epithelial cells (T84) | GlcNAc | Not Binding | 17156748 |
| Clostridium botulinum | HA | Mannose | Monosaccharides | Intestinal epithelial cells (T84) | Man | Not Binding | 17156748 |
