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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source ▲ | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Propionibacterium freudenreichii | Unknown | Lactosylceramide (Lactocerebroside) | Diosylceramides | Human erythrocytes, Whole dog small intestine | Gal(b1-4)Glc(b1-1)Cer | Binding | 2452754 |
| Helicobacter pylori | BabA (blood group antigen binding adhesin) | Fucosylated Lewis b (Leb) histoblood group antigens | Oligosaccharides | Human gastric epithelium | Binding | 9430586 | |
| Helicobacter pylori | Adhesins | GM3(NeuAc) | Monosialoglycosphingolipids | Human gastric mucosa | NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2037054 |
| Helicobacter pylori | Adhesins | Sulfatide (CSE) | Sulfoglycosphingolipids | Human gastric mucosa | HSO3(-3)Gal(b1-1)Cer | Binding | 2037054 |
| Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Human granulocytes | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 9228091 |
| Helicobacter mustelae | Lectin-hemagglutinin adhesins | Acid glycosphingolipids | Acidic Glycosphingolipids | Human granulocytes | Binding | 12704182 | |
| Helicobacter pylori | Lectin-hemagglutinin adhesins | Acid glycosphingolipids | Acidic Glycosphingolipids | Human granulocytes | Binding | 12704182 | |
| Helicobacter hepaticus | Lectin-hemagglutinin adhesins | Acid glycosphingolipids | Acidic Glycosphingolipids | Human granulocytes | Binding | 12704182 | |
| Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | GM3(NeuAc) | Monosialoglycosphingolipids | Human granulocytes | NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9228091 |
| Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | Sialyl-3-Paragloboside (S-3-PG; α2,3-sialylparagloboside) | Monosialoglycosphingolipids | Human granulocytes | NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9228091 |
| Helicobacter pylori | 35S-labeled or 125I-labeled proteins | Lactosylceramide (d18:1-16:0/24:1) | Diosylceramides | Human granulocytes, Human erythrocytes | Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9499377 |
| Influenza virus | Residues 226 (leucine) and 228 (serine) | Sialic acid α2,6Galβ1,4GalNAc | Oligosaccharides | Human isolates | NeuAc(a2-6)Gal(b1-4)GalNAc | Binding | 7975212 |
| Escherichia coli | F1C | Galactosylceramide (t18:0-h22:0-h24:0) | Monoglycosylceramides | Human kidney | Gal(b1-1)Cer | Binding | 11877427 |
| Actinomyces viscosus | Unknown | unnamed ligand | Oligoglycosylceramides | Human kidney | GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Shigella dysenteriae | B subunit | unnamed ligand | Oligoglycosylceramides | Human kidney | GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 3543013 |
| Actinomyces naeslundii | Unknown | unnamed ligand | Oligoglycosylceramides | Human kidney | GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Shigella dysenteriae | B subunit | SSEA-3 (GSL) (Galactosyl globoside; Gb5) | Oligoglycosylceramides | Human kidney | Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 3543013 |
| Escherichia coli | F1C | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) (t18:0-h20:0-h24:0) | Oligoglycosylceramides | Human kidney tissues | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 11877427 |
| Escherichia coli | PrsG (class III) | DSGG (Disialosyl galactosyl globoside, disialyl Gb5) | Disialoglycosphingolipids | Human kidney tissues | NeuAc(a2-3)Gal(b1-3)[NeuAc(a2-6)]GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9673272 |
| Escherichia coli | PapG (class I) | DSGG (Disialosyl galactosyl globoside, disialyl Gb5) | Disialoglycosphingolipids | Human kidney tissues | NeuAc(a2-3)Gal(b1-3)[NeuAc(a2-6)]GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9673272 |
| Escherichia coli | P-fimbriae | DSGG (Disialosyl galactosyl globoside, disialyl Gb5) | Disialoglycosphingolipids | Human kidney tissues | NeuAc(a2-3)Gal(b1-3)[NeuAc(a2-6)]GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9673272 |
| Escherichia coli | PapG (class II) | DSGG (Disialosyl galactosyl globoside, disialyl Gb5) | Disialoglycosphingolipids | Human kidney tissues | NeuAc(a2-3)Gal(b1-3)[NeuAc(a2-6)]GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9673272 |
| Escherichia coli | PrsG (class III) | SSEA-4 (GSL) (Sialosyl galactosyl globoside; SGG; sialyl Gb5) | Monosialoglycosphingolipids | Human kidney tissues | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9673272 |
| Escherichia coli | PapG (class I) | SSEA-4 (GSL) (Sialosyl galactosyl globoside; SGG; sialyl Gb5) | Monosialoglycosphingolipids | Human kidney tissues | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9673272 |
| Escherichia coli | P-fimbriae | SSEA-4 (GSL) (Sialosyl galactosyl globoside; SGG; sialyl Gb5) | Monosialoglycosphingolipids | Human kidney tissues | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9673272 |
