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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature ▲ | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Foot-and-mouth disease virus | VP1 protein (RGD motif) | αvβ3 Integrin | Glycoproteins | BHK-21/LLC-MK2/HeLa/BK-LF | Binding | 7533862 | |
| Staphylococcus aureus | Unknown | MUC16 mucin | Glycoproteins | Human corneal-limbal epithelial(HCLE) cells | Binding | 17898272 | |
| Entamoeba histolytica | Raft-like plasma membrane domains | β-2 and β-7 integrins | Glycoproteins | Intestinal cells | Binding | 15322032 | |
| Reovirus | Unknown | Junctional adhesion molecule A (JAM-A) | Glycoproteins | Most organs including the central nervous system/heart/liver | Binding | 18216114 | |
| Paracoccidioides brasiliensis | Paracoccin | Laminin | Glycoproteins | Binding | 16476564 | ||
| Staphylococcus aureus | FnbA | Fibronectin | Glycoproteins | Binding | 10341176 | ||
| Streptococcus gordonii | CshB | Fibronectin | Glycoproteins | Binding | 10341176 | ||
| Escherichia coli | FimH | Tamm-Horsfall protein (THP) | Glycoproteins | Binding | 12010488 | ||
| Escherichia coli | FimH | Fibronectin | Glycoproteins | Binding | 12010488 | ||
| Escherichia coli | FimH | Laminin | Glycoproteins | Binding | 12010488 | ||
| Streptococcus gordonii | CshaB (Antigen I/II) | Fibronectin | Glycoproteins | Binding | 12640357 | ||
| Escherichia coli | Type 1-fimbriae | alpha-Mannosyl groups on glycoproteins | Glycoproteins | Binding | 11454740 | ||
| Klebsiella pneumoniae | MrkD-pili | Collagen (type V) | Glycoproteins | Binding | 10341176 | ||
| Klebsiella pneumoniae | MrkD-pili | Collagen (type V) | Glycoproteins | Binding | 12640357 | ||
| Escherichia coli | Type 1-pili | Tamm-Horsfall protein (THP) | Glycoproteins | Binding | 12010488 | ||
| Escherichia coli | Type 1-pili | Fibronectin | Glycoproteins | Binding | 12010488 | ||
| Escherichia coli | Type 1-pili | Laminin | Glycoproteins | Binding | 12010488 | ||
| Bordetella pertussis | Pertussis toxin | Haptoglobin | Glycoproteins | Binding | 1729677 | ||
| Anaplasma phagocytophilum | "P-selectin mimic, MSP2" | Fucosylated PSGL-1 (P-selectin glycoprotein ligand-1) | Glycoproteins | Binding | 16299269 | ||
| Borrelia burgdorferi | BBK32 | Fibronectin | Glycoproteins | Binding | 18833295 | ||
| Staphylococcus aureus | FnbB | Fibronectin | Glycoproteins | Binding | 12640357 | ||
| Streptococcus pneumoniae | PspC (Lary family) (alias: SpsA/CbpA/PbcA/Hic) | C3 and complement factor H | Glycoproteins | Binding | 12640357 | ||
| Streptococcus pneumoniae | PspC (Lary family) (alias: SpsA/CbpA/PbcA/Hic) | IgA | Glycoproteins | Binding | 12640357 | ||
| Staphylococcus aureus | FnbB | Fibronectin | Glycoproteins | Binding | 10341176 | ||
| Streptococcus pneumoniae | SpsA | IgA | Glycoproteins | Binding | 10341176 |
