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MIRAGE
Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature ▲ | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Escherichia coli | S-fimbriae | NeuAcα3Galβ-containing glycoproteins | Glycoproteins | Lumenal surfaces of the vascular endothelium in the neonatal rat brain | NeuAc(a2-3)Gal(b | Binding | 15973004 |
| Escherichia coli | SfaS | NeuAcα3Galβ-containing glycoproteins | Glycoproteins | Lumenal surfaces of the vascular endothelium in the neonatal rat brain | NeuAc(a2-3)Gal(b | Binding | 15973004 |
| Equine rhinitis A virus | Viral protein | NeuAc/GlcNAc/(GlcNAc)n side chains of WGA-binding glycoproteins | Glycoproteins | Feline kidney(CRFK)/Equine fetal kidney(EFK)/Mouse(McCoy)/Rabbit kidney(RK-13) | NeuAc/GlcNAc/(GlcNAc)n | Binding | 15302947 |
| Equine rhinitis A virus | Viral protein | NeuAcα2,3-Gal/GalNAc side chains of MAA-binding glycoproteins | Glycoproteins | Feline kidney(CRFK)/Equine fetal kidney(EFK)/Mouse(McCoy)/Rabbit kidney(RK-13) | NeuAc(a2-3)Gal/GalNAc | Binding | 15302947 |
| Norovirus | Unknown | Lewis b (Leb-HSA) | Glycoproteins | Human serum albumin | Fuc(a1-2)Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(c)-APD | Binding | 19054801 |
| Equine rhinitis A virus | Viral protein | α-mannose and α-glucose side chains of ConA-binding glycoproteins | Glycoproteins | Feline kidney(CRFK)/Equine fetal kidney(EFK)/Mouse(McCoy)/Rabbit kidney(RK-13) | Man/Glc | Binding | 15302947 |
| Paracoccidioides brasiliensis | Adhesins | Fibrinogen | Glycoproteins | Human type II alveolar cells (A549) | Binding | 18083324 | |
| Neisseria meningitidis | Type 4-pili | Agglutinin glycoproteins containing O-/N-linked (poly)lactosamine and hybrid oligosaccharides | Glycoproteins | Human saliva | Binding | 16177210 | |
| Mycoplasma pneumoniae | Adhesins | hCG (human chorionic gonadotropin) | Glycoproteins | Erythrocytes | Binding | 2470754 | |
| Bordetella pertussis | FimD | VLA-5 (very late activation antigen 5) | Glycoproteins | Monocytes | Binding | 11348687 | |
| Foot-and-mouth disease virus | VP1 protein (RGD motif) | αvβ3 Integrin | Glycoproteins | BHK-21/LLC-MK2/HeLa/BK-LF | Binding | 7533862 | |
| Staphylococcus aureus | Unknown | MUC16 mucin | Glycoproteins | Human corneal-limbal epithelial(HCLE) cells | Binding | 17898272 | |
| Reovirus | Unknown | Junctional adhesion molecule A (JAM-A) | Glycoproteins | Most organs including the central nervous system/heart/liver | Binding | 18216114 | |
| Adeno-associated virus | Unknown | Glycoprotein with α2,6 N-linked sialic acid | Glycoproteins | NeuAc(a2-6)Gal(b1-4)GlcNAc | Binding | 16940521 | |
| Streptococcus pneumoniae | SpsA | IgA | Glycoproteins | Binding | 10341176 | ||
| Escherichia coli | CsgA (curli) | Human contact phase proteins | Glycoproteins | Binding | 9973330 | ||
| Escherichia coli | Type 1-fimbriae | alpha-Mannosyl groups on glycoproteins | Glycoproteins | Binding | 11454740 | ||
| Bordetella pertussis | Pertussis toxin | Haptoglobin | Glycoproteins | Binding | 1729677 | ||
| Salmonella enteritidis | AgfA (curli) | Human contact phase proteins | Glycoproteins | Binding | 9973330 | ||
| Streptococcus pneumoniae | PspC (Lary family) (alias: SpsA/CbpA/PbcA/Hic) | IgA | Glycoproteins | Binding | 12640357 | ||
| Fusobacterium nucleatum | Lectin-like proteins (adhesin) | Mr 36,900 PRG (Proline-Rich Glycoprotein) | Glycoproteins | Binding | 1894623 | ||
| Staphylococcus epidermidis | 17-kDa HBP (Heparin-binding protein) | Thrombospondin (TSP) | Glycoproteins | Binding | 11393292 | ||
| Fusobacterium nucleatum | Lectin-like proteins (adhesin) | Mr 89,000 PRG (Proline-Rich Glycoprotein) | Glycoproteins | Binding | 1894623 | ||
| Bordetella pertussis | PT (subunit S2 of B oligomer) | Haptoglobin | Glycoproteins | Binding | 1729677 | ||
| Staphylococcus haemolyticus | 17-kDa HBP (Heparin-binding protein) | Thrombospondin (TSP) | Glycoproteins | Binding | 11393292 |
