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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source ▲ | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Lactobacillus johnsonii | Unknown | Lc4Cer (Lactotetraosylceramide) | Oligoglycosylceramides | Human meconium | Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 11087711 |
| Actinomyces naeslundii | Unknown | Lc4Cer (Lactotetraosylceramide) | Oligoglycosylceramides | Human meconium | Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2358461 |
| Shigella dysenteriae | B subunit | unnamed ligand | Glycosphingolipids | Human meconium | Fuc(a1-2)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 3543013 |
| Actinomyces viscosus | Unknown | unnamed ligand | Glycosphingolipids | Human meconium | Fuc(a1-2)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Actinomyces naeslundii | Unknown | unnamed ligand | Glycosphingolipids | Human meconium | Fuc(a1-2)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | Sialyl-6-Paragloboside (S-6-PG; α2,6-sialylparagloboside) | Monosialoglycosphingolipids | Human meconium | NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9228091 |
| Actinomyces viscosus | Unknown | Gb2 (Galabiosylceramide) | Diosylceramides | Human meconium | Gal(a1-4)Gal(b1-1)Cer | Not Binding | 2358461 |
| Actinomyces naeslundii | Unknown | Gb2 (Galabiosylceramide) | Diosylceramides | Human meconium | Gal(a1-4)Gal(b1-1)Cer | Not Binding | 2358461 |
| Escherichia coli | F1C | Lewis a (Lea) (GSL) | Glycosphingolipids | Human meconium | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11877427 |
| Actinomyces viscosus | Unknown | unnamed ligand | Oligoglycosylceramides | Human meconium | GalNAc(a1-3)Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Actinomyces viscosus | Unknown | unnamed ligand | Oligoglycosylceramides | Human meconium | GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | Lc4Cer (Lactotetraosylceramide) | Oligoglycosylceramides | Human meconium | Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9228091 |
| Shigella dysenteriae | B subunit | Lc4Cer (Lactotetraosylceramide) | Oligoglycosylceramides | Human meconium | Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 3543013 |
| Actinomyces naeslundii | Unknown | unnamed ligand | Oligoglycosylceramides | Human meconium | GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Helicobacter pylori | HPNAP (neutrophil-activating protein of H. pylori) | Acid glycosphingolipids | Acidic Glycosphingolipids | Human neutrophil granulocytes | Binding | 11087709 | |
| Helicobacter pylori | SabA (sialic acid-binding adhesin) | Sialic acid | Monosaccharides | Human neutrophils | Binding | 15689619 | |
| Escherichia coli | F1C | Lactosylceramide (d18:1-16:0/24:1) | Diosylceramides | Human neutrophils | Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11877427 |
| Escherichia coli | F1C | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Human neutrophils | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11877427 |
| Streptococcus gordonii | Hsa | Sialic acid | Monosaccharides | Human oral cavity (erythrocytes and polymorphonuclear leukocytes) | Binding | 16177339 | |
| Streptococcus gordonii | SspA/SspB (AgI/II family) | Salivary glycoprotein (gp340) | Glycoproteins | Human oral cavity (in fluid and surface-associated phases) | Binding | 16177339 | |
| Streptococcus gordonii | Hsa | Salivary glycoprotein (gp340) | Glycoproteins | Human oral cavity (surface-bound) | Binding | 16177339 | |
| Streptococcus gordonii | Adhesins | PMN (polymorphonuclear leukocytes) surface glycoproteins in the presence of sialic acid | Glycoproteins | Human peripheral blood buffy coat cells | Binding | 11035744 | |
| Actinomyces naeslundii | Adhesins | PMN (polymorphonuclear leukocytes) surface glycoproteins | Glycoproteins | Human peripheral blood buffy coat cells | Binding | 11035744 | |
| Moraxella catarrhalis | Fimbriae | GM2(NeuAc) | Monosialoglycosphingolipids | Human pharyngeal epithelial cells | GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 12137200 |
| Moraxella catarrhalis | Fimbriae | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Human pharyngeal epithelial cells | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 12137200 |
