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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature ▲ | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Borrelia burgdorferi | "DbpA, DbpB, Bgp" | Dermatan sulfate | Glycosaminoglycans | Binding | 16299269 | ||
| Helicobacter pylori | Unknown | Heparan sulfate | Glycosaminoglycans | Binding | 16088272 | ||
| Bordetella pertussis | Fim2 (H1/H2) | Heparin | Glycosaminoglycans | ECM | Binding | 11348687 | |
| Foot-and-mouth disease virus | VP1 (RGD peptide) | Heparin | Glycosaminoglycans | Extracellular matrix (ECM) | Binding | 9557639 | |
| Bordetella pertussis | FHA (442-863) | Heparin | Glycosaminoglycans | WiDr cells, HeLa cells, Vero cells, Extracellular matrix (ECM) | Binding | 11348687 | |
| Bordetella pertussis | FHA (442-863) | Heparin | Glycosaminoglycans | Respiratory epithelial cells | Binding | 17106803 | |
| Foot-and-mouth disease virus | Natural ligand of integrin [alpha]v[beta]3 | Heparin | Glycosaminoglycans | Extracellular matrix (ECM) | Binding | 8764038 | |
| Herpes simplex virus | Unknown | Heparin | Glycosaminoglycans | Human cervical cells | Binding | 9420059 | |
| Borrelia burgdorferi | BBK32 | Heparin | Glycosaminoglycans | Mammalian cell surface | Binding | 16368999 | |
| Borrelia burgdorferi | BBK32 | GAGs (glycosaminoglycans) | Glycosaminoglycans | Binding | 18833295 | ||
| Herpes virus | gH/gL | GAGs (glycosaminoglycans) | Glycosaminoglycans | Binding | 18301747 | ||
| Herpes virus | gp70 | GAGs (glycosaminoglycans) | Glycosaminoglycans | Binding | 18301747 | ||
| Borrelia burgdorferi | "DbpA, DbpB, Bgp" | Heparin | Glycosaminoglycans | Binding | 16299269 | ||
| Borrelia burgdorferi | Unknown | Chondroitin 6-sulfate (C-6S) | Glycosaminoglycans | Vero cells | Not Binding | 9826395 | |
| Borrelia burgdorferi | Unknown | Heparan sulfate (fraction: HS-A) | Glycosaminoglycans | Vero cells | Not Binding | 9826395 | |
| Borrelia burgdorferi | Unknown | Heparan sulfate (fraction: HS-A) | Glycosaminoglycans | Vero cells | Not Binding | 9826395 | |
| Borrelia burgdorferi | Unknown | Heparan sulfate (fraction: HS-A) | Glycosaminoglycans | Vero cells | Not Binding | 9826395 | |
| Borrelia burgdorferi | Unknown | Heparan sulfate (fraction: HS-A) | Glycosaminoglycans | Vero cells | Not Binding | 9826395 | |
| Foot-and-mouth disease virus | VP1 (RGD peptide) | Heparan sulfate (independent of expression of αvβ3 Integrin on cell-sulface) | Glycosaminoglycans | Extracellular matrix (ECM) | Binding | 9557639 | |
| Foot-and-mouth disease virus | VP1 (RGD peptide) | Heparan sulfate (independent of expression of αvβ3 Integrin on cell-sulface) | Glycosaminoglycans | Extracellular matrix (ECM) | Binding | 9557639 | |
| Foot-and-mouth disease virus | VP1 (RGD peptide) | Heparan sulfate (independent of expression of αvβ3 Integrin on cell-sulface) | Glycosaminoglycans | Extracellular matrix (ECM) | Binding | 9557639 | |
| Foot-and-mouth disease virus | VP1 (RGD peptide) | Heparan sulfate (independent of expression of αvβ3 Integrin on cell-sulface) | Glycosaminoglycans | Extracellular matrix (ECM) | Binding | 9557639 | |
| Borrelia burgdorferi | Unknown | Heparin (N-desulfated, N-acetylated) | Glycosaminoglycans | Vero cells | Binding | 9826395 | |
| Foot-and-mouth disease virus | Natural ligand of integrin [alpha]v[beta]3 | De-N-sulfated heparin | Glycosaminoglycans | Extracellular matrix (ECM) | Not Binding | 8764038 | |
| Human immunodeficiency virus | Unknown | NAC-heparin (non-anticoagulant heparin) | Glycosaminoglycans | Human T cells | Binding | 9420059 |
