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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature ▲ | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Escherichia coli | P-fimbriae | Gal alpha 1-4 Gal-containing isoreceptors | Glycosphingolipids | Pyelonephritis patients | Gal(a1-4)Gal | Binding | |
| Escherichia coli | P-pili | Globo-series GSL | Glycosphingolipids | Uroepithelial cells, Erythrocytes | Gal(a1-4)Gal | Binding | 9973330 |
| Escherichia coli | PapG | Globo-series GSL | Glycosphingolipids | Uroepithelial cells, Erythrocytes | Gal(a1-4)Gal | Binding | 9973330 |
| Escherichia coli | PapG (class I) G adhesins | Gal alpha 1-4 Gal-containing isoreceptors | Glycosphingolipids | Pyelonephritis patients | Gal(a1-4)Gal | Binding | |
| Escherichia coli | F1C | Lewis a (Lea) (GSL) | Glycosphingolipids | Human meconium | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11877427 |
| Neisseria gonorrhoeae | Lectin-like proteins (adhesin) | Lewis a (Lea) (GSL) | Glycosphingolipids | Gonorrhoeae patients | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2468365 |
| Propionibacterium granulosum | Lectin-like proteins (adhesin) | Lewis a (Lea) (GSL) | Glycosphingolipids | Human skin | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2468365 |
| Actinomyces viscosus | Unknown | unnamed ligand | Glycosphingolipids | Human meconium | Fuc(a1-2)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Lactobacillus johnsonii | Unknown | Lewis a (Lea) (GSL) | Glycosphingolipids | Human small intestine | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11087711 |
| Shigella dysenteriae | B subunit | unnamed ligand | Glycosphingolipids | Human meconium | Fuc(a1-2)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 3543013 |
| Actinomyces naeslundii | Unknown | unnamed ligand | Glycosphingolipids | Human meconium | Fuc(a1-2)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Helicobacter pylori | Adhesins | PGCs (polyglycosyl ceramides) | Glycosphingolipids | Human leukocytes, Human neutrophils | Binding | 10569742 | |
| Helicobacter pylori | Unknown | PGCs (polyglycosyl ceramides) | Glycosphingolipids | Human erythrocytes, Human leukocytes, Human placenta | Binding | 9169796 | |
| Helicobacter pylori | Unknown | PGCs (polyglycosyl ceramides) | Glycosphingolipids | Rat small intestine, Wild boar intestine, Monkey intestine | Binding | 9169796 | |
| Pseudomonas aeruginosa | PA-IIL | Lewis a (Lea) (GSL) | Glycosphingolipids | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 16762477 | |
| Helicobacter mustelae | Lectin-hemagglutinin adhesins | Lewis a (Lea) (GSL) | Glycosphingolipids | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 12704182 | |
| Helicobacter bilis | Lectin-hemagglutinin adhesins | Lewis a (Lea) (GSL) | Glycosphingolipids | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 12704182 | |
| Helicobacter pylori | Lectin-hemagglutinin adhesins | Lewis a (Lea) (GSL) | Glycosphingolipids | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 12704182 | |
| Escherichia coli | K88ab/K88ac/K88ad | Lewis a (Lea) (GSL) | Glycosphingolipids | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11953368 | |
| Helicobacter hepaticus | Lectin-hemagglutinin adhesins | Lewis a (Lea) (GSL) | Glycosphingolipids | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 12704182 | |
| Helicobacter felis | Lectin-hemagglutinin adhesins | Lewis a (Lea) (GSL) | Glycosphingolipids | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 12704182 | |
| Shigella dysenteriae | Shiga toxin | unnamed ligand | Glycosphingolipids | Fuc(a1-2)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2435422 | |
| Norovirus | Unknown | Lewis a (Lea) (GSL) | Glycosphingolipids | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 18701592 | |
| Norovirus | Unknown | Lewis a (Lea) (GSL) | Glycosphingolipids | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 18701592 | |
| Helicobacter canis | Lectin-hemagglutinin adhesins | Lewis a (Lea) (GSL) | Glycosphingolipids | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 12704182 |
