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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source ▲ | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Actinomyces naeslundii | Unknown | unnamed ligand | Polyglycosylceramides | Rat small intestine | GalNAc(b1-3)[Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 2358461 |
| Shigella dysenteriae | B subunit | Gal-Gb3 | Oligoglycosylceramides | Rat small intestine | Gal(a1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 3543013 |
| Actinomyces viscosus | Unknown | unnamed ligand | Polyglycosylceramides | Rat small intestine | GalNAc(b1-3)[Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Actinomyces viscosus | Unknown | unnamed ligand | Oligoglycosylceramides | Rat small intestine | [Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Shigella dysenteriae | B subunit | isoGb4 (Isoglobotetraosylceramide; iGb4) | Oligoglycosylceramides | Rat small intestine | GalNAc(b1-3)Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 3543013 |
| Shigella dysenteriae | B subunit | unnamed ligand | Oligoglycosylceramides | Rat small intestine | [Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer *n=2-5 | Not Binding | 3543013 |
| Actinomyces naeslundii | Unknown | unnamed ligand | Oligoglycosylceramides | Rat small intestine | [Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Shigella dysenteriae | B subunit | unnamed ligand | Polyglycosylceramides | Rat small intestine | GalNAc(b1-3)[Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer *n=1-5 | Not Binding | 3543013 |
| Helicobacter pylori | Unknown | PGCs (polyglycosyl ceramides) | Glycosphingolipids | Rat small intestine, Wild boar intestine, Monkey intestine | Binding | 9169796 | |
| Bordetella pertussis | CRD (carbohydrate recognition domain) of Fha (Filamentous Hemagglutinin) | Lactosylceramide (Lactocerebroside) | Diosylceramides | Respiratory ciliated cells, Alveolar macrophages | Gal(b1-4)Glc(b1-1)Cer | Binding | 8514379 |
| Streptococcus pyogenes | Protein F (Antigen I/II) | Fibronectin | Glycoproteins | Respiratory endothelial cells | Binding | 10341176 | |
| Streptococcus pyogenes | Sfbl (Antigen I/II) | Fibronectin | Glycoproteins | Respiratory endothelial cells | Binding | 10341176 | |
| Bordetella pertussis | FHA (442-863) | Heparin | Glycosaminoglycans | Respiratory epithelial cells | Binding | 17106803 | |
| Streptococcus pyogenes | Protein F (Antigen I/II) | Fibronectin | Glycoproteins | Respiratory epithelial cells | Binding | 1385871 | |
| Streptococcus pyogenes | Sfbl (Antigen I/II) | Fibronectin | Glycoproteins | Respiratory epithelial cells | Binding | 12640357 | |
| Streptococcus pyogenes | Protein F (Antigen I/II) | Fibronectin | Glycoproteins | Respiratory epithelial cells | Binding | 12640357 | |
| Bordetella pertussis | Iron-induced surface-exposed proteins | Mucin | Glycoproteins | Respiratory epithelial cells (A549) | Binding | 17727651 | |
| Bordetella pertussis | Iron-induced surface-exposed proteins | Sialic acid | Monosaccharides | Respiratory epithelial cells (A549) | Binding | 17727651 | |
| Klebsiella pneumoniae | Unknown | Mannose | Monosaccharides | Respiratory tract | Man | Binding | 16564136 |
| Pseudomonas aeruginosa | Unknown | Fucose | Monosaccharides | Respiratory tract | Fuc | Binding | 16564136 |
| Haemophilus influenzae | Unknown | Tetrasaccharides | Oligosaccharides | Respiratory tract | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc | Binding | 16564136 |
| Pseudomonas aeruginosa | Unknown | unnamed ligand | Oligosaccharides | Respiratory tract | Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc | Binding | 16564136 |
| Streptococcus pneumoniae | Unknown | Tetrasaccharides | Oligosaccharides | Respiratory tract | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc | Binding | 16564136 |
| Streptococcus suis | Unknown | unnamed ligand | Oligosaccharides | Respiratory tract | Gal(a1-4)Gal(b1-4)Glc | Binding | 16564136 |
| Neisseria meningitidis | Unknown | Tetrasaccharides | Oligosaccharides | Respiratory tract | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc | Binding | 16564136 |
