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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source ▲ | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Burkholderia cepacia | Lectin-like proteins (adhesin) | Gb2 (Galabiosylceramide) | Diosylceramides | Sputa of cystic fibrosis patients | Gal(a1-4)Gal(b1-1)Cer | Binding | 8606110 |
| Burkholderia cepacia | Lectin-like proteins (adhesin) | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Sputa of cystic fibrosis patients | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 8606110 |
| Burkholderia cepacia | Lectin-like proteins (adhesin) | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Sputa of cystic fibrosis patients | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 8606110 |
| Helicobacter pylori | Unknown | unnamed ligand | Oligosaccharides | Stomach | NeuAc(a2-3)Gal(b1-4)GlcNAc | Binding | 16564136 |
| Pseudomonas aeruginosa | Adhesins | MUC1 mucin | Glycoproteins | Surface of chinese hamster ovary (CHO) cells | Binding | 11133508 | |
| Clostridium tetani | Tetanus toxin (Hc fragment) | GT1b analog | Trisialoglycosphingolipids | Synapse | Binding | 18809496 | |
| Clostridium tetani | Unknown | GT1b analog | Trisialoglycosphingolipids | Synapse | Binding | 18809496 | |
| Escherichia coli | F1C | Gb2 (Galabiosylceramide) | Diosylceramides | Synthetic | Gal(a1-4)Gal(b1-1)Cer | Not Binding | 11877427 |
| Actinomyces odontolyticus | Unknown | unknown carbohydrate ligand | Saccharides | Tongue | Binding | 9712794 | |
| Actinomyces odontolyticus | Type 2-fimbriae | β-linked galactosamine | Saccharides | Tongue | GalNAc(b | Not Binding | 9712794 |
| Streptococcus sobrinus | SpaA (Antigen I/II Family) | Salivary glycoprotein | Glycoproteins | Tooth surface | Binding | 10341176 | |
| Streptococcus mutans | P1 (Antigen I/II) | Salivary glycoprotein | Glycoproteins | Tooth surface | Binding | 10341176 | |
| Streptococcus sanguis | SsaB (Lral family) | Salivary glycoprotein | Glycoproteins | Tooth surface | Binding | 10341176 | |
| Streptococcus gordonii | SspA (Antigen I/II) | Salivary glycoprotein | Glycoproteins | Tooth surface | Binding | 10341176 | |
| Streptococcus mutans | SpaP (Antigen I/II Family) | Salivary glycoprotein | Glycoproteins | Tooth surface | Binding | 10341176 | |
| Streptococcus mutans | Pac (Antigen I/II) | Salivary glycoprotein | Glycoproteins | Tooth surface | Binding | 10341176 | |
| Streptococcus sobrinus | Pag (Antigen I/II) | Salivary glycoprotein | Glycoproteins | Tooth surface | Binding | 10341176 | |
| Streptococcus mutans | Ag I/II (Antigen I/II Family) | Salivary glycoprotein | Glycoproteins | Tooth surface | Binding | 10341176 | |
| Streptococcus gordonii | SspB (Antigen I/II) | Salivary glycoprotein | Glycoproteins | Tooth surface | Binding | 10341176 | |
| Streptococcus parasanguinis | FimA (Lral family); localized to the tip of peritrichous surface fimbria | Salivary glycoprotein | Glycoproteins | Tooth surface | Binding | 10341176 | |
| Streptococcus pneumoniae | Adhesins | N-Acetylgalactosamine | Monosaccharides | Type-II lung cells, Vascular endothelial cells | GalNAc | Binding | 7752878 |
| Streptococcus pneumoniae | Adhesins | D-Mannose | Monosaccharides | Type-II lung cells, Vascular endothelial cells | Man | Binding | 7752878 |
| Streptococcus pneumoniae | Adhesins | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Type-II lung cells, Vascular endothelial cells | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 7752878 |
| Streptococcus pneumoniae | Adhesins | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | Type-II lung cells, Vascular endothelial cells | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 7752878 |
| Streptococcus pneumoniae | Adhesins | Gb5 (Forssman glycolipid) | Oligoglycosylceramides | Type-II lung cells, Vascular endothelial cells | GalNAc(a1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 7752878 |
