PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
Source | Last Updated |
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Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
Species | Pathogen Adherence Molecule ▼ | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
---|---|---|---|---|---|---|---|
Escherichia coli | PrsG (class III) | Glucosylceramide | Monoglycosylceramides | Colonic adenocarcinoma | Glc(b1-1)Cer | Not Binding | 9673272 |
Escherichia coli | PrsG (class III) | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Human erythrocytes | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9673272 |
Escherichia coli | PrsG | Gal alpha 1-4 Gal-containing glicolipids | Glycolipids | Gal(a1-4)Gal | Binding | 12640357 | |
Escherichia coli | PrsG | Gal(a1-4)Gal in globo-series of glycolipids | Glycosphingolipids | Gal(a1-4)Gal | Binding | 10341176 | |
Streptococcus pyogenes | Protein F (Antigen I/II) | Fibronectin | Glycoproteins | Respiratory endothelial cells | Binding | 10341176 | |
Streptococcus pyogenes | Protein F (Antigen I/II) | Fibronectin | Glycoproteins | Respiratory epithelial cells | Binding | 1385871 | |
Streptococcus pyogenes | Protein F (Antigen I/II) | Fibronectin | Glycoproteins | Respiratory epithelial cells | Binding | 12640357 | |
Clostridium botulinum | Progenitor toxin (type A) | Lactose | Disaccharides | Intestine-407 cells | Gal(b1-4)Glc | Binding | 15850798 |
Clostridium botulinum | Progenitor toxin (type A) | N-acetyllactosamine (LacNAc) | Disaccharides | Intestine-407 cells | Gal(b1-4)GlcNAc | Binding | 15850798 |
Neisseria meningitidis | PorA | C4b-binding protein (C4bp) | Glycoproteins | Serum | Binding | 15879129 | |
Mycoplasma gallisepticum | PlpA (pneumoniae-like protein; P65) | Fibronectin | Glycoproteins | Binding | 16495551 | ||
Pseudomonas aeruginosa | Pili | unnamed ligand | Disaccharides | GalNAc(b1-4)Gal | Binding | 8574698 | |
Helicobacter pylori | Phe147 in HpaA (Helicobacter pylori adhesin A) | Lactosylceramide (Lactocerebroside) | Diosylceramides | Gal(b1-4)Glc(b1-1)Cer | Binding | 16953581 | |
Bordetella pertussis | Pertussis toxin | Fetuin | Glycoproteins | Bovine | Binding | 14532091 | |
Bordetella pertussis | Pertussis toxin | Fetuin | Glycoproteins | Binding | 1729677 | ||
Bordetella pertussis | Pertussis toxin | Gangliosides | Sialoglycosphingolipids | Human alveolar macrophages | Binding | 1729677 | |
Bordetella pertussis | Pertussis toxin | Lactosylceramide (Lactocerebroside) | Diosylceramides | Human cilia of the respiratory epithelium | Gal(b1-4)Glc(b1-1)Cer | Binding | 1729677 |
Bordetella pertussis | Pertussis toxin | Glucosylceramide | Monoglycosylceramides | Human cilia of the respiratory epithelium | Glc(b1-1)Cer | Binding | 1729677 |
Bordetella pertussis | Pertussis toxin | Haptoglobin | Glycoproteins | Binding | 1729677 | ||
Escherichia coli | Pertactin | Mannose oligosaccharides | Oligosaccharides | Man | Binding | 10341176 | |
Bordetella pertussis | Pertactin | Integrins | Glycoproteins | Binding | 10341176 | ||
Bordetella pertussis | Pertactin | Integrins | Glycoproteins | Binding | 12640357 | ||
Bordetella pertussis | Pertactin | unknown carbohydrate ligand | Saccharides | Eukaryotic cells | Binding | 11348687 | |
Vibrio cholerae | Pentameric B-subunit | GD1b | Disialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 9038159 | |
Vibrio cholerae | Pentameric B-subunit | GM1 | Monosialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 9038159 |
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Last updated: August 19, 2024