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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule ▼ | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Reovirus | sigma 1 proteins | Sialic acid | Monosaccharides | Murine intestine, Murine spleen, Murine liver, Murine brain, Human cholangiocarcinoma cells | Binding | 12813018 | |
| Escherichia coli | hLT | Blood group A antigen analog | Oligosaccharides | Binding | 18809496 | ||
| Herpes virus | gp70 | GAGs (glycosaminoglycans) | Glycosaminoglycans | Binding | 18301747 | ||
| Human immunodeficiency virus | gp120 | Sulfatide (CSE) | Sulfoglycosphingolipids | Human U373-MG glioma and SK-N-MC neuroblastoma cells, Human colon epithelial HT29 cells | HSO3(-3)Gal(b1-1)Cer | Binding | 15973004 |
| Human immunodeficiency virus | gp120 | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Human colonic epithelial cell lines (HT-29/HT-29-A7/HT-29-D4) | Gal(b1-1)Cer | Binding | 8464878 |
| Human immunodeficiency virus | gp120 | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Human U373-MG glioma and SK-N-MC neuroblastoma cells, Human colon epithelial HT29 cells | Gal(b1-1)Cer | Binding | 15973004 |
| Herpes virus | gH/gL | GAGs (glycosaminoglycans) | Glycosaminoglycans | Binding | 18301747 | ||
| Pseudomonas aeruginosa | exoenzyme S | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Epithelial cells | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9224879 |
| Pseudomonas aeruginosa | exoenzyme S | Phosphatidylethanolamine (PE) | Non-glycosylated Lipids | Epithelial cells | Binding | 9224879 | |
| Pseudomonas aeruginosa | exoenzyme S | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Epithelial cells | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9224879 |
| Sporothrix schenckii | Yeast cells and hyphae | Fibronectin | Glycoproteins | Extracellular matrix (ECM) | Binding | 15351036 | |
| Sporothrix schenckii | Yeast cells and hyphae | Laminin | Glycoproteins | Extracellular matrix (ECM) | Binding | 15351036 | |
| Sporothrix schenckii | Yeast cells and conidia | Fibronectin | Glycoproteins | Extracellular matrix (ECM) | Binding | 11598061 | |
| Rotavirus | Virus Spike Protein VP4 (mapped between aminoacids 93 and 208 of its trypsin cleavage fragment VP8) | Sialic acid-containing cell compounds | Glycoconjugates | Binding | 9261399 | ||
| Equine rhinitis A virus | Viral protein | NeuAc/GlcNAc/(GlcNAc)n side chains of WGA-binding glycoproteins | Glycoproteins | Feline kidney(CRFK)/Equine fetal kidney(EFK)/Mouse(McCoy)/Rabbit kidney(RK-13) | NeuAc/GlcNAc/(GlcNAc)n | Binding | 15302947 |
| Equine rhinitis A virus | Viral protein | NeuAcα2,3-Gal/GalNAc side chains of MAA-binding glycoproteins | Glycoproteins | Feline kidney(CRFK)/Equine fetal kidney(EFK)/Mouse(McCoy)/Rabbit kidney(RK-13) | NeuAc(a2-3)Gal/GalNAc | Binding | 15302947 |
| Equine rhinitis A virus | Viral protein | α-mannose and α-glucose side chains of ConA-binding glycoproteins | Glycoproteins | Feline kidney(CRFK)/Equine fetal kidney(EFK)/Mouse(McCoy)/Rabbit kidney(RK-13) | Man/Glc | Binding | 15302947 |
| Escherichia coli | Verotoxin (2) | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 3284526 | |
| Escherichia coli | Verotoxin (1; B-subunit) | CD77 (Globotriaosylceramide; Gb3) | Oligoglycosylceramides | Germinal center B lymphocytes, Burkitt's lymphoma cells | Gal(a1-4)Gal | Binding | 7516406 |
| Escherichia coli | Verotoxin (1/2c) | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 12628483 | |
| Escherichia coli | Verotoxin (1) | unnamed ligand | Oligosaccharides | Gal(a1-4)Gal(b1-4)Glc(b | Binding | 8574698 | |
| Escherichia coli | Verotoxin | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 3298243 | |
| Escherichia coli | Verotoxin | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 15973004 | |
| Rotavirus | VP8 (spike protein) | Sialic acid(2-O-methyl-α-Neu5Gc (Neu5Gc2Me)) | Monosaccharides | Binding | 17306299 | ||
| Rotavirus | VP8 (spike protein) | Sialic acid | Monosaccharides | Binding | 17277447 |
