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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule ▼ | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Mumps virus | MuV-HN | Glycans containing α2,3-linked sialic acid | Oligosaccharides | NeuAc(a2-3)Gal(b1-4)GlcNAc | Binding | 27671656 | |
| Mumps virus | MuV-HN | Glycans containing α2,3-linked sialic acid | Oligosaccharides | NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-2)[NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-4)]Man(a1-3)[NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-2)[NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-6)]Man(a1-6)]Man(b1-4)GlcNAc(b1-4)GlcNAc | Not Binding | 27671656 | |
| Mumps virus | MuV-HN | Glycans containing α2,6-linked sialic acid | Oligosaccharides | NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-3)[NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)GlcNAc | Not Binding | 27671656 | |
| Mumps virus | MuV-HN | Glycans containing α2,3-linked sialic acid | Oligosaccharides | NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-2)[NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-4]Man(a1-3)[NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)GlcNAc | Binding | 27671656 | |
| Klebsiella pneumoniae | MrkD-pili | Collagen (type V) | Glycoproteins | Binding | 10341176 | ||
| Klebsiella pneumoniae | MrkD-pili | Collagen (type V) | Glycoproteins | Binding | 12640357 | ||
| Entamoeba histolytica | Membrane-associated lectins (heavy(170-kDa)/light(35-or31-kDa) subunits) | N-Acetylgalactosamine | Monosaccharides | GalNAc | Binding | 10225860 | |
| Entamoeba histolytica | Membrane-associated lectins (heavy(170-kDa)/light(35-or31-kDa) subunits) | Galactose | Monosaccharides | Gal | Binding | 10225860 | |
| Vibrio cholerae | MSHA (mannose/glucose-specific hemagglutinin) | Mannose | Monosaccharides | Patient with acute watery diarrhea | Man | Binding | 10219594 |
| Vibrio cholerae | MSHA (mannose/glucose-specific hemagglutinin) | Glucose | Monosaccharides | Patient with acute watery diarrhea | Glc | Binding | 10219594 |
| Leptospira interrogans | Lsa24 | Laminin | Glycoproteins | Extracellular matrix (ECM) | Binding | 16954400 | |
| Burkholderia cepacia | Lectin-like proteins (adhesin) | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Sputa of cystic fibrosis patients | Gal(b1-1)Cer | Binding | 8606110 |
| Burkholderia cepacia | Lectin-like proteins (adhesin) | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Sputa of cystic fibrosis patients | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 8606110 |
| Neisseria gonorrhoeae | Lectin-like proteins (adhesin) | isoGb3 (Isoglobotriaosylceramide; iGb3) | Oligoglycosylceramides | Gonorrhoeae patients | Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2468365 |
| Neisseria gonorrhoeae | Lectin-like proteins (adhesin) | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Gonorrhoeae patients | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 2468365 |
| Propionibacterium granulosum | Lectin-like proteins (adhesin) | isoGb3 (Isoglobotriaosylceramide; iGb3) | Oligoglycosylceramides | Human skin | Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2468365 |
| Propionibacterium granulosum | Lectin-like proteins (adhesin) | Fucosyl Asialo GM1 | Oligoglycosylceramides | Human skin | Fuc(a1-2)Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 2468365 |
| Propionibacterium granulosum | Lectin-like proteins (adhesin) | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Human skin | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 2468365 |
| Propionibacterium granulosum | Lectin-like proteins (adhesin) | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Human skin | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2468365 |
| Fusobacterium nucleatum | Lectin-like proteins (adhesin) | unnamed ligand | Oligosaccharides | Gal(b1-4)GlcNAc | Binding | 1894623 | |
| Fusobacterium nucleatum | Lectin-like proteins (adhesin) | unnamed ligand | Oligosaccharides | Gal(b1-3)GalNAc | Binding | 1894623 | |
| Burkholderia cepacia | Lectin-like proteins (adhesin) | Gb2 (Galabiosylceramide) | Diosylceramides | Sputa of cystic fibrosis patients | Gal(a1-4)Gal(b1-1)Cer | Binding | 8606110 |
| Neisseria gonorrhoeae | Lectin-like proteins (adhesin) | Gb2 (Galabiosylceramide) | Diosylceramides | Gonorrhoeae patients | Gal(a1-4)Gal(b1-1)Cer | Not Binding | 2468365 |
| Neisseria gonorrhoeae | Lectin-like proteins (adhesin) | Lewis a (Lea) (GSL) | Glycosphingolipids | Gonorrhoeae patients | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2468365 |
| Propionibacterium granulosum | Lectin-like proteins (adhesin) | Lewis a (Lea) (GSL) | Glycosphingolipids | Human skin | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2468365 |
