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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source ▲ | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Helicobacter pylori | 35S-labeled or 125I-labeled proteins | Gb5 (Forssman glycolipid) | Oligoglycosylceramides | Dog small intestine | GalNAc(a1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9499377 |
| Actinomyces viscosus | Unknown | Gb5 (Forssman glycolipid) | Oligoglycosylceramides | Dog small intestine | GalNAc(a1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Actinomyces viscosus | Unknown | A6 type 2 glycosphingolipid (A6-2) | Oligoglycosylceramides | Dog small intestine | GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Actinomyces viscosus | Unknown | unnamed ligand | Oligoglycosylceramides | Dog small intestine | Fuc(a1-2)Gal(b1-4)GlcNAc(b1-3)Gal(b1-3)Glc(b1-1)Cer | Not Binding | 2358461 |
| Actinomyces viscosus | Unknown | Lewis x (Lex) (GSL) | Oligoglycosylceramides | Dog small intestine | Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Actinomyces viscosus | Unknown | unnamed ligand | Oligoglycosylceramides | Dog small intestine | GalNAc(a1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Lactobacillus johnsonii | Unknown | Gb5 (Forssman glycolipid) | Oligoglycosylceramides | Dog small intestine | GalNAc(a1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11087711 |
| Shigella dysenteriae | B subunit | Gb5 (Forssman glycolipid) | Oligoglycosylceramides | Dog small intestine | GalNAc(a1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 3543013 |
| Shigella dysenteriae | B subunit | A6 type 2 glycosphingolipid (A6-2) | Oligoglycosylceramides | Dog small intestine | GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 3543013 |
| Actinomyces naeslundii | Unknown | Gb5 (Forssman glycolipid) | Oligoglycosylceramides | Dog small intestine | GalNAc(a1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Actinomyces naeslundii | Unknown | unnamed ligand | Oligoglycosylceramides | Dog small intestine | GalNAc(a1-3)Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Actinomyces naeslundii | Unknown | A6 type 2 glycosphingolipid (A6-2) | Oligoglycosylceramides | Dog small intestine | GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Actinomyces naeslundii | Unknown | unnamed ligand | Oligoglycosylceramides | Dog small intestine | Fuc(a1-2)Gal(b1-4)GlcNAc(b1-3)Gal(b1-3)Glc(b1-1)Cer | Not Binding | 2358461 |
| Actinomyces naeslundii | Unknown | Lewis x (Lex) (GSL) | Oligoglycosylceramides | Dog small intestine | Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Actinomyces naeslundii | Unknown | unnamed ligand | Oligoglycosylceramides | Dog small intestine | GalNAc(a1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Bordetella pertussis | Fim2 (H1/H2) | Heparin | Glycosaminoglycans | ECM | Binding | 11348687 | |
| Escherichia coli | K1 | unnamed ligand | Disaccharides | Endothelial cells | GlcNAc(b1-4)GlcNAc | Binding | 16564136 |
| Neisseria meningitidis | OpcA | Sialic acid-containing polysaccharides | Polysaccharides | Epithelial cells | Binding | 18076035 | |
| Pseudomonas aeruginosa | Type 4-pili | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Epithelial cells | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9224879 |
| Pseudomonas aeruginosa | exoenzyme S | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Epithelial cells | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9224879 |
| Pseudomonas aeruginosa | Flagellin | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Epithelial cells | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9224879 |
| Foot-and-mouth disease virus | RGD motif of the VP1 GH loop | αvβ6 Integrin | Glycoproteins | Epithelial cells | Binding | 10799568 | |
| Pseudomonas aeruginosa | Flagellin | MUC1 mucin | Glycoproteins | Epithelial cells | Binding | 11880301 | |
| Pseudomonas aeruginosa | exoenzyme S | Phosphatidylethanolamine (PE) | Non-glycosylated Lipids | Epithelial cells | Binding | 9224879 | |
| Pseudomonas aeruginosa | Type 4-pili | Lactosylceramide (Lactocerebroside) | Diosylceramides | Epithelial cells | Gal(b1-4)Glc(b1-1)Cer | Binding | 9224879 |
