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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name ▲ | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Clostridium botulinum | Botulinum neurotoxin (16S) | Mannose | Monosaccharides | Intestinal epithelial cells (T84) | Man | Not Binding | 17156748 |
| Clostridium botulinum | HA | Mannose | Monosaccharides | Intestinal epithelial cells (T84) | Man | Not Binding | 17156748 |
| Listeria innocua | Unknown | Mannose 6-phosphate insulin-like growth factor-II receptor (M6P/IGF-IIR) | Glycoproteins | Fetal calf serum | Binding | 16369013 | |
| Listeria monocytogenes | Unknown | Mannose 6-phosphate insulin-like growth factor-II receptor (M6P/IGF-IIR) | Glycoproteins | Fetal calf serum | Binding | 16369013 | |
| Escherichia coli | FimH | Mannose oligosaccharides | Oligosaccharides | Eukaryotic cells | Man | Binding | 12640357 |
| Escherichia coli | FimH | Mannose oligosaccharides | Oligosaccharides | Man | Binding | 10341176 | |
| Escherichia coli | Type 1-pili | Mannose oligosaccharides | Oligosaccharides | Man | Binding | 9973330 | |
| Escherichia coli | Pertactin | Mannose oligosaccharides | Oligosaccharides | Man | Binding | 10341176 | |
| Escherichia coli | FimG/FimH | Mannose oligosaccharides | Oligosaccharides | Man | Binding | 9973330 | |
| Escherichia coli | Type 1-fimbriae | Mannose-derived neoglycoproteins and dendrimers | Glycoproteins | Man | Binding | 16564136 | |
| Escherichia coli | FimH | Mannotriose | Oligosaccharides | Man(a1-3)[Man(a1-6)]Man | Binding | 12010488 | |
| Escherichia coli | Type 1-pili | Mannotriose | Oligosaccharides | Man(a1-3)[Man(a1-6)]Man | Binding | 12010488 | |
| Pseudomonas aeruginosa | PA-IL (51-kDa) | Melibiose | Disaccharides | Gal(a1-6)Glc | Binding | 15049333 | |
| Pseudomonas aeruginosa | PA-IL | Melibiose | Disaccharides | Gal(a1-6)Glc | Binding | 10967261 | |
| Pseudomonas aeruginosa | PA-IL | Methyl-α-Gal | Monosaccharides | Binding | 10967261 | ||
| Pseudomonas aeruginosa | PA-IL | Methyl-β-Gal | Monosaccharides | Binding | 10967261 | ||
| Influenza virus | SNA lectins | Minor NeuAcα6-containing molecules | Glycoconjugates | Human leukocytes | Binding | 11030743 | |
| Helicobacter pylori | Unknown | Mono-N-propionylated S-3-PG (paragloboside) | Glycosphingolipids | Binding | 15659615 | ||
| Helicobacter pylori | Unknown | Mono-de-N-acetylated S-3-PG (paragloboside) | Glycosphingolipids | Binding | 15659615 | ||
| Helicobacter pylori | Unknown | Monohexyl ceramides (MHCer) | Glycolipids | Binding | 16088272 | ||
| Fusobacterium nucleatum | Lectin-like proteins (adhesin) | Mr 36,900 PRG (Proline-Rich Glycoprotein) | Glycoproteins | Binding | 1894623 | ||
| Fusobacterium nucleatum | Lectin-like proteins (adhesin) | Mr 89,000 PRG (Proline-Rich Glycoprotein) | Glycoproteins | Binding | 1894623 | ||
| Escherichia coli | K99 | Mucin | Glycoproteins | Intestinal cells | Binding | 7849044 | |
| Bordetella pertussis | Iron-induced surface-exposed proteins | Mucin | Glycoproteins | Respiratory epithelial cells (A549) | Binding | 17727651 | |
| Campylobacter upsaliensis | Unknown | Mucin | Glycoproteins | Human small intestine | Binding | 8926069 |
