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Repository for lectin-assisted multimodality data
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MIRAGE
Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name ▲ | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Vibrio harveyi | CBP (chitin-binding proteins) 53-kDa | N-Acetylglucosamine | Monosaccharides | GlcNAc | Binding | 10049907 | |
| Clostridium botulinum | Botulinum neurotoxin (16S) | N-Acetylglucosamine | Monosaccharides | Intestinal epithelial cells (T84) | GlcNAc | Not Binding | 17156748 |
| Clostridium botulinum | HA | N-Acetylglucosamine | Monosaccharides | Intestinal epithelial cells (T84) | GlcNAc | Not Binding | 17156748 |
| Escherichia coli | NeuC protein of K1 capsule (UDP GlcNAc 2-epimerase)) | N-Acetylglucosamine | Monosaccharides | GlcNAc | Not Binding | 14729696 | |
| Pasteurella haemolytica | 68-kDa proteins | N-Acetylneuraminic acid | Monosaccharides | Bronchial lavages of sheep with pneumonic pasteurelosis | NeuAc | Binding | 10570221 |
| Human immunodeficiency virus | Unknown | N-acetyl-b-maltoheptaosylamine sulfate (SM) | Oligosaccharides | Human T cells | Binding | 9420059 | |
| Chlamydia trachomatis | Unknown | N-acetyl-b-maltoheptaosylamine sulfate (SM) | Oligosaccharides | HeLa cells | Binding | 9420059 | |
| Herpes simplex virus | Unknown | N-acetyl-b-maltoheptaosylamine sulfate (SM) | Oligosaccharides | Human cervical cells | Binding | 9420059 | |
| Streptococcus pneumoniae | PsaA (Lary family) | N-acetylhexosamine-galactose | Disaccharides | Binding | 12640357 | ||
| Clostridium botulinum | Progenitor toxin (type A) | N-acetyllactosamine (LacNAc) | Disaccharides | Intestine-407 cells | Gal(b1-4)GlcNAc | Binding | 15850798 |
| Neisseria gonorrhoeae | Unknown | N-acetyllactosamine (LacNAc) | Disaccharides | Genitalium | Gal(b1-4)GlcNAc | Binding | 16564136 |
| Clostridium botulinum | Unknown | N-acetyllactosamine (LacNAc) | Disaccharides | Intestine-407 cells | Gal(b1-4)GlcNAc | Binding | 15850798 |
| Helicobacter pylori | Fibrillar hemmagglutinin | N-acetylneuraminyl-a(2-3)-galactopyranosyl sequence | Glycoproteins | Gastric epithelium, Mucus layer of the stomach | NeuAc(a2-3)Gal | Binding | 2459065 |
| Hepatitis virus | Unknown | N-linked glycans | N-glycans | Binding | 11530212 | ||
| Plasmodium falciparum | Unknown | N-linked oligosaccharides of glycophorins | Oligosaccharides | Binding | 8574698 | ||
| Rubulavirus | Unknown | N-linked sialylated glycoproteins | Glycoproteins | Pig neurons, glial cells | Binding | 16459111 | |
| Human immunodeficiency virus | Unknown | NAC-heparin (non-anticoagulant heparin) | Glycosaminoglycans | Human T cells | Binding | 9420059 | |
| Chlamydia trachomatis | Unknown | NAC-heparin (non-anticoagulant heparin) | Glycosaminoglycans | HeLa cells | Binding | 9420059 | |
| Herpes simplex virus | Unknown | NAC-heparin (non-anticoagulant heparin) | Glycosaminoglycans | Human cervical cells | Binding | 9420059 | |
| Neisseria gonorrhoeae | Unknown | NAC-heparin (non-anticoagulant heparin) | Glycosaminoglycans | Human epithelial cells | Binding | 9420059 | |
| Escherichia coli | K88 | Neoglycans (PSA-Lac) | Glycoproteins | Porcine serum albumin(PSA) | Binding | 19101589 | |
| Streptococcus suis | Unknown | Neoglycoproteins (containing P1 Antigen) | Glycoproteins | Gal(a1-4)Gal(b1-4)GlcNAc | Binding | 8440715 | |
| Streptococcus suis | Unknown | Neoglycoproteins (containing Pk Antigen) | Glycoproteins | Gal(a1-4)Gal(b1-4)Glc | Binding | 8440715 | |
| Mycoplasma pneumoniae | Unknown | NeuAc-SLex (GSL) (Sialylneolactofucopentaosylcer) | Monosialoglycosphingolipids | Human colon adenocarcinoma cells (WiDr ) | NeuAc(a2-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2470753 |
| Rotavirus | Unknown | NeuAc-SLex (GSL) (Sialylneolactofucopentaosylcer) | Monosialoglycosphingolipids | NeuAc(a2-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 11160731 |
