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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule ▲ | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Streptococcus gordonii | Adhesins | Fetuin | Glycoproteins | HL-60 promyelocytic leukemia cell line | Binding | 11035744 | |
| Cryptococcus neoformans | Adhesins | Sucrose | Monosaccharides | Human lung epithelial cell line (A549) | Binding | 9453390 | |
| Cryptococcus neoformans | Adhesins | Inositol | Non-glycosylated Lipids | Human lung epithelial cell line (A549) | Binding | 9453390 | |
| Helicobacter pylori | Adhesins | Blood group Lewis b (Leb) antigen | Oligosaccharides | Binding | 8018146 | ||
| Legionella pneumophila | Adhesins | GD1a | Disialoglycosphingolipids | Human epithelial cells (respiratory tract) | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Not Binding | 14687561 |
| Legionella pneumophila | Adhesins | GM3(NeuAc) | Monosialoglycosphingolipids | Human epithelial cells (respiratory tract) | NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 14687561 |
| Streptococcus gordonii | Adhesins | Sialic acid | Monosaccharides | HL-60 promyelocytic leukemia cell line, Leukosialin (CD43) | Binding | 11035744 | |
| Helicobacter pylori | Adhesins | Gangliosides | Sialoglycosphingolipids | Human leukocytes, Human neutrophils | Binding | 10569742 | |
| Histoplasma capsulatum | Adhesins | Lactosylceramide (Lactocerebroside) | Diosylceramides | Phagocytes | Gal(b1-4)Glc(b1-1)Cer | Binding | 19547878 |
| Bordetella pertussis | Adhesins | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Human lung, Human trachea | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 1918002 |
| Streptococcus pneumoniae | Adhesins | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Type-II lung cells, Vascular endothelial cells | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 7752878 |
| Streptococcus suis | Adhesins | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Erythrocytes | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 7961660 |
| Burkholderia pseudomallei | Adhesins | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Pharyngeal epithelial cells | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 10497993 |
| Legionella pneumophila | Adhesins | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Human epithelial cells (respiratory tract) | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 14687561 |
| Neisseria gonorrhoeae | Adhesins | unnamed ligand | Oligosaccharides | Mucos membranes of the genitourinary tract/rectum/oropharynx/conjunctiva | Gal(b1-4)GlcNAc(b1-4)Gal(b1-4)Glc | Binding | 2115881 |
| Streptococcus suis | Adhesins | Gb2 (Galabiosylceramide) | Diosylceramides | Gal(a1-4)Gal(b1-1)Cer | Binding | 7961660 | |
| Streptococcus pneumoniae | Adhesins | unnamed ligand | Disaccharides | GalNAc(b1-4)Gal | Binding | 6886624 | |
| Shigella dysenteriae | Adhesins | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 11381327 | |
| Bordetella parapertussis | Adhesins | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 1918002 | |
| Neisseria gonorrhoeae | Adhesins | Lactotriaosylceramide (Lc3) | Oligoglycosylceramides | GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2115881 | |
| Paracoccidioides brasiliensis | Adhesins | Fibronectin | Glycoproteins | Human type II alveolar cells (A549) | Binding | 18083324 | |
| Paracoccidioides brasiliensis | Adhesins | Fibrinogen | Glycoproteins | Human type II alveolar cells (A549) | Binding | 18083324 | |
| Mycoplasma pneumoniae | Adhesins | Laminin | Glycoproteins | Murine Engelbreth Holm Swarm tumor, Murine erythrocytes | Binding | 2470754 | |
| Mycoplasma pneumoniae | Adhesins | hCG (human chorionic gonadotropin) | Glycoproteins | Erythrocytes | Binding | 2470754 | |
| Helicobacter pylori | Adhesins | PGCs (polyglycosyl ceramides) | Glycosphingolipids | Human leukocytes, Human neutrophils | Binding | 10569742 |
