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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name ▲ | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Haemophilus influenzae | Unknown | Tetrasaccharides | Oligosaccharides | Respiratory tract | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc | Binding | 16564136 |
| Streptococcus pneumoniae | Unknown | Tetrasaccharides | Oligosaccharides | Respiratory tract | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc | Binding | 16564136 |
| Neisseria meningitidis | Unknown | Tetrasaccharides | Oligosaccharides | Respiratory tract | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc | Binding | 16564136 |
| Streptococcus pneumoniae | Unknown | Tetrasaccharides | Oligosaccharides | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc | Binding | 16564136 | |
| Staphylococcus epidermidis | 17-kDa HBP (Heparin-binding protein) | Thrombospondin (TSP) | Glycoproteins | Binding | 11393292 | ||
| Staphylococcus haemolyticus | 17-kDa HBP (Heparin-binding protein) | Thrombospondin (TSP) | Glycoproteins | Binding | 11393292 | ||
| Neisseria meningitidis | Type 4-pili | Thyroglobulin containing N-linked complex and hybrid (oligomannosidic) glycans | Glycoproteins | Bovine | Binding | 16177210 | |
| Streptococcus pneumoniae | Unknown | Trisaccharides | Oligosaccharides | GlcNAc(b1-3)Gal(b1-4)Glc | Binding | 16564136 | |
| Escherichia coli | FimH | Uroplakins 1a and 1b containing a single N-linked carbohydrate of the high-mannose type | Glycoproteins | Binding | 12010488 | ||
| Escherichia coli | Type 1-pili | Uroplakins 1a and 1b containing a single N-linked carbohydrate of the high-mannose type | Glycoproteins | Binding | 12010488 | ||
| Bordetella pertussis | FimD | VLA-5 (very late activation antigen 5) | Glycoproteins | Monocytes | Binding | 11348687 | |
| Escherichia coli | PapG | alpha-D-galactopyranosyl-(1-4)-beta-D-galactopyranose | Disaccharides | Uroepithelial cells | Gal(a1-4)Gal | Binding | 2886993 |
| Escherichia coli | Type 1-fimbriae | alpha-Mannosyl groups on glycoproteins | Glycoproteins | Binding | 11454740 | ||
| Pseudomonas aeruginosa | LecB | alpha-methyl-fucoside | Monosaccharides | A549 cells | Binding | 19237519 | |
| Escherichia coli | S-fimbriae | alpha-sialyl-beta-2,3-galactose-containing glycolipids and glycoproteins | Glycoconjugates | NeuAc(a2-3)Gal(b | Binding | 2883653 | |
| Neisseria meningitidis | 33-kDa proteins | factor H (fH) | Glycoproteins | Binding | 16751403 | ||
| Mycoplasma pneumoniae | Adhesins | hCG (human chorionic gonadotropin) | Glycoproteins | Erythrocytes | Binding | 2470754 | |
| Propionibacterium granulosum | Unknown | isoGb3 (Isoglobotriaosylceramide; iGb3) | Oligoglycosylceramides | Whole dog small intestine | Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2452754 |
| Helicobacter pylori | 35S-labeled or 125I-labeled proteins | isoGb3 (Isoglobotriaosylceramide; iGb3) | Oligoglycosylceramides | Dog small intestine | Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 9499377 |
| Escherichia coli | F1C | isoGb3 (Isoglobotriaosylceramide; iGb3) | Oligoglycosylceramides | Cat intestine | Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 11877427 |
| Neisseria gonorrhoeae | Lectin-like proteins (adhesin) | isoGb3 (Isoglobotriaosylceramide; iGb3) | Oligoglycosylceramides | Gonorrhoeae patients | Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2468365 |
| Propionibacterium granulosum | Lectin-like proteins (adhesin) | isoGb3 (Isoglobotriaosylceramide; iGb3) | Oligoglycosylceramides | Human skin | Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2468365 |
| Actinomyces viscosus | Unknown | isoGb3 (Isoglobotriaosylceramide; iGb3) | Oligoglycosylceramides | Dog small intestine | Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2358461 |
| Lactobacillus johnsonii | Unknown | isoGb3 (Isoglobotriaosylceramide; iGb3) | Oligoglycosylceramides | Dog small intestine | Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 11087711 |
| Actinomyces naeslundii | Unknown | isoGb3 (Isoglobotriaosylceramide; iGb3) | Oligoglycosylceramides | Dog small intestine | Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2358461 |
