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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name ▲ | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Helicobacter mustelae | Lectin-hemagglutinin adhesins | isoGb3 (Isoglobotriaosylceramide; iGb3) | Oligoglycosylceramides | Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 12704182 | |
| Helicobacter bilis | Lectin-hemagglutinin adhesins | isoGb3 (Isoglobotriaosylceramide; iGb3) | Oligoglycosylceramides | Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 12704182 | |
| Helicobacter pylori | Lectin-hemagglutinin adhesins | isoGb3 (Isoglobotriaosylceramide; iGb3) | Oligoglycosylceramides | Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 12704182 | |
| Helicobacter hepaticus | Lectin-hemagglutinin adhesins | isoGb3 (Isoglobotriaosylceramide; iGb3) | Oligoglycosylceramides | Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 12704182 | |
| Helicobacter felis | Lectin-hemagglutinin adhesins | isoGb3 (Isoglobotriaosylceramide; iGb3) | Oligoglycosylceramides | Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 12704182 | |
| Neisseria gonorrhoeae | Unknown | isoGb3 (Isoglobotriaosylceramide; iGb3) | Oligoglycosylceramides | Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 12628483 | |
| Helicobacter canis | Lectin-hemagglutinin adhesins | isoGb3 (Isoglobotriaosylceramide; iGb3) | Oligoglycosylceramides | Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 12704182 | |
| Propionibacterium granulosum | Unknown | isoGb3 (Isoglobotriaosylceramide; iGb3) | Oligoglycosylceramides | Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2435422 | |
| Shigella dysenteriae | B subunit | isoGb3 (Isoglobotriaosylceramide; iGb3) | Oligoglycosylceramides | Dog small intestine | Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 3543013 |
| Shigella dysenteriae | Shiga toxin | isoGb3 (Isoglobotriaosylceramide; iGb3) | Oligoglycosylceramides | Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2435422 | |
| Rotavirus | Unknown | isoGb3 (Isoglobotriaosylceramide; iGb3) | Oligoglycosylceramides | Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11160731 | |
| Escherichia coli | Unknown | isoGb3 (Isoglobotriaosylceramide; iGb3) | Oligoglycosylceramides | Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2435422 | |
| Shigella dysenteriae | Unknown | isoGb3 (Isoglobotriaosylceramide; iGb3) | Oligoglycosylceramides | Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2435422 | |
| Propionibacterium freudenreichii | Unknown | isoGb3 (Isoglobotriaosylceramide; iGb3) | Oligoglycosylceramides | Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2435422 | |
| Actinomyces naeslundii | Unknown | isoGb4 (Isoglobotetraosylceramide; iGb4) | Oligoglycosylceramides | Rat colon carcinoma | GalNAc(b1-3)Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2358461 |
| Helicobacter pylori | 35S-labeled or 125I-labeled proteins | isoGb4 (Isoglobotetraosylceramide; iGb4) | Oligoglycosylceramides | Rat colon carcinoma | GalNAc(b1-3)Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9499377 |
| Escherichia coli | F1C | isoGb4 (Isoglobotetraosylceramide; iGb4) | Oligoglycosylceramides | Rat intestine | GalNAc(b1-3)Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11877427 |
| Neisseria gonorrhoeae | Lectin-like proteins (adhesin) | isoGb4 (Isoglobotetraosylceramide; iGb4) | Oligoglycosylceramides | Gonorrhoeae patients | GalNAc(b1-3)Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2468365 |
| Propionibacterium granulosum | Lectin-like proteins (adhesin) | isoGb4 (Isoglobotetraosylceramide; iGb4) | Oligoglycosylceramides | Human skin | GalNAc(b1-3)Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2468365 |
| Actinomyces viscosus | Unknown | isoGb4 (Isoglobotetraosylceramide; iGb4) | Oligoglycosylceramides | Rat colon carcinoma | GalNAc(b1-3)Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Shigella dysenteriae | B subunit | isoGb4 (Isoglobotetraosylceramide; iGb4) | Oligoglycosylceramides | Rat small intestine | GalNAc(b1-3)Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 3543013 |
| Streptococcus pneumoniae | CBPs (choline-binding proteins) | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Cytokine-activated cells | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 12640357 |
| Streptococcus pneumoniae | Unknown | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Chinchilla tracheal epithelium | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 10090858 |
| Neisseria gonorrhoeae | Adhesins | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Mucos membranes of the genitourinary tract/rectum/oropharynx/conjunctiva | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2115881 |
| Streptococcus pneumoniae | CbpA; SpsA; PbcA; PspC (CBPs) | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Cytokine activated epithelial and endothelial cells | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 10341176 |
