Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Salmonella enteritidis | AgfA (curli) | Human contact phase proteins | Glycoproteins | Binding | 9973330 | ||
| Bordetella pertussis | PT (subunit S2 of B oligomer) | Haptoglobin | Glycoproteins | Binding | 1729677 | ||
| Escherichia coli | Type 1-fimbriae | alpha-Mannosyl groups on glycoproteins | Glycoproteins | Binding | 11454740 | ||
| Staphylococcus haemolyticus | 17-kDa HBP (Heparin-binding protein) | Thrombospondin (TSP) | Glycoproteins | Binding | 11393292 | ||
| Streptococcus pneumoniae | SpsA | IgA | Glycoproteins | Binding | 10341176 | ||
| Escherichia coli | CsgA (curli) | Human contact phase proteins | Glycoproteins | Binding | 9973330 | ||
| Fusobacterium nucleatum | Lectin-like proteins (adhesin) | Mr 36,900 PRG (Proline-Rich Glycoprotein) | Glycoproteins | Binding | 1894623 | ||
| Hepatitis virus | Unknown | N-linked glycans | N-glycans | Binding | 11530212 | ||
| Rotavirus | DLP (Double-layered virus particles) | Asialo gangliosides | Neutral Glycosphingolipids | Binding | 10659372 | ||
| Semliki forest virus | Unknown | Sphingomyelin | Non-glycosylated Lipids | Binding | 8574698 | ||
| New world arenavirus | Glycoprotein (GP) | O-mannosyl glycans on alpha-dystroglycan (DG) | O-glycans | Binding | 17360738 | ||
| Escherichia coli | hLT | Blood group A antigen analog | Oligosaccharides | Binding | 18809496 | ||
| Influenza virus | Unknown | Endothelial cell-specific molecule (ESM) | Proteoglycans | Not Binding | 1740131 | ||
| Borrelia burgdorferi | "DbpA, DbpB, Bgp" | Decorin | Proteoglycans | Binding | 16299269 | ||
| Anaplasma marginale | "MSP1a, MSP1b, MSP2" | unknown carbohydrate ligand | Saccharides | Binding | 16299269 |
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