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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source ▲ | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Actinomyces naeslundii | Unknown | unnamed ligand | Sialoglycosphingolipids | Frog brain | Gal(b1-3)[NeuAc(a2-6)]GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 2358461 |
| Escherichia coli | Shiga-like toxin (Stx1) | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | GI/kidney | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 18809496 |
| Escherichia coli | Unknown | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | GI/kidney | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 18809496 |
| Helicobacter pylori | SabA (sialic acid-binding adhesin) | Sialyl Lewis x (SLex) antigen | Oligosaccharides | Gastric epithelial progenitors (GEPs) | NeuAc(a2-3)Gal(b1-4) | Binding | 16406776 |
| Helicobacter pylori | HpaA | Sialyl Lewis x (SLex) antigen | Oligosaccharides | Gastric epithelial progenitors (GEPs) | NeuAc(a2-3)Gal(b1-4) | Binding | 16406776 |
| Helicobacter pylori | HP0721 | Sialyl Lewis x (SLex) antigen | Oligosaccharides | Gastric epithelial progenitors (GEPs) | NeuAc(a2-3)Gal(b1-4) | Binding | 16406776 |
| Helicobacter pylori | Fibrillar hemmagglutinin | N-acetylneuraminyl-a(2-3)-galactopyranosyl sequence | Glycoproteins | Gastric epithelium, Mucus layer of the stomach | NeuAc(a2-3)Gal | Binding | 2459065 |
| Neisseria gonorrhoeae | Unknown | N-acetyllactosamine (LacNAc) | Disaccharides | Genitalium | Gal(b1-4)GlcNAc | Binding | 16564136 |
| Escherichia coli | Verotoxin (1; B-subunit) | CD77 (Globotriaosylceramide; Gb3) | Oligoglycosylceramides | Germinal center B lymphocytes, Burkitt's lymphoma cells | Gal(a1-4)Gal | Binding | 7516406 |
| Escherichia coli | Unknown | CD77 (Globotriaosylceramide; Gb3) | Oligoglycosylceramides | Germinal center B lymphocytes, Burkitt's lymphoma cells | Gal(a1-4)Gal | Binding | 7516406 |
| Borrelia afzelii | Unknown | Dermatan sulfate | Glycosaminoglycans | Glial cells | Binding | 10085013 | |
| Borrelia burgdorferi | Unknown | Dermatan sulfate | Glycosaminoglycans | Glial cells | Binding | 10085013 | |
| Plasmodium falciparum | Unknown | Sialic acid | Monosaccharides | Glycophorins A/B on the erythrocyte membrane | Binding | 3308959 | |
| Neisseria gonorrhoeae | Lectin-like proteins (adhesin) | isoGb3 (Isoglobotriaosylceramide; iGb3) | Oligoglycosylceramides | Gonorrhoeae patients | Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2468365 |
| Neisseria gonorrhoeae | Lectin-like proteins (adhesin) | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Gonorrhoeae patients | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 2468365 |
| Neisseria gonorrhoeae | Lectin-like proteins (adhesin) | Gb2 (Galabiosylceramide) | Diosylceramides | Gonorrhoeae patients | Gal(a1-4)Gal(b1-1)Cer | Not Binding | 2468365 |
| Neisseria gonorrhoeae | Lectin-like proteins (adhesin) | Lewis a (Lea) (GSL) | Glycosphingolipids | Gonorrhoeae patients | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2468365 |
| Neisseria gonorrhoeae | Lectin-like proteins (adhesin) | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Gonorrhoeae patients | Gal(b1-1)Cer | Not Binding | 2468365 |
| Neisseria gonorrhoeae | Lectin-like proteins (adhesin) | Glucosylceramide | Monoglycosylceramides | Gonorrhoeae patients | Glc(b1-1)Cer | Not Binding | 2468365 |
| Neisseria gonorrhoeae | Lectin-like proteins (adhesin) | Fucosyl Asialo GM1 | Oligoglycosylceramides | Gonorrhoeae patients | Fuc(a1-2)Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2468365 |
| Neisseria gonorrhoeae | Lectin-like proteins (adhesin) | H5 type 2 pentaglycosylceramide (neolacto-series) | Oligoglycosylceramides | Gonorrhoeae patients | Fuc(a1-2)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2468365 |
| Neisseria gonorrhoeae | Lectin-like proteins (adhesin) | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Gonorrhoeae patients | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2468365 |
| Neisseria gonorrhoeae | Lectin-like proteins (adhesin) | isoGb4 (Isoglobotetraosylceramide; iGb4) | Oligoglycosylceramides | Gonorrhoeae patients | GalNAc(b1-3)Gal(a1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2468365 |
| Neisseria gonorrhoeae | Lectin-like proteins (adhesin) | H5 type 1 pentaglycosylceramide (lacto-series) | Oligoglycosylceramides | Gonorrhoeae patients | Fuc(a1-2)Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2468365 |
| Neisseria gonorrhoeae | Lectin-like proteins (adhesin) | Lc4Cer (Lactotetraosylceramide) | Oligoglycosylceramides | Gonorrhoeae patients | Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2468365 |
