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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name ▲ | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Salmonella milwaukee | Unknown | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 3413084 | |
| Actinomyces naeslundii | Adhesins | Asialofetuin | Glycoproteins | HL-60 promyelocytic leukemia cell line | Binding | 11035744 | |
| Vibrio cholerae | Cholera toxin | B-GM1 | Monosialoglycosphingolipids | Gal(a1-3)[Fuc(a1-2)]Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 7527546 | |
| Vibrio cholerae | Unknown | B-GM1 | Monosialoglycosphingolipids | Gal(a1-3)[Fuc(a1-2)]Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 7527546 | |
| Lactobacillus johnsonii | Unknown | B6 type 2 glycosphingolipid (B6-2) | Oligoglycosylceramides | Human erythrocytes | Gal(a1-3)[Fuc(a1-2)]Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11087711 |
| Shigella dysenteriae | B subunit | B6 type 2 glycosphingolipid (B6-2) | Oligoglycosylceramides | Human erythrocytes | Gal(a1-3)[Fuc(a1-2)]Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 3543013 |
| Staphylococcus haemolyticus | 17-kDa HBP (Heparin-binding protein) | Basic fibroblast growth factor (bFGF) | Glycoproteins | Binding | 11393292 | ||
| Staphylococcus epidermidis | 17-kDa HBP (Heparin-binding protein) | Basic fibroblast growth factor (bFGF) | Glycoproteins | Binding | 11393292 | ||
| Cytomegalovirus | Unknown | Bis-sulfogangliotriaosylceramide (SB2) | Sulfoglycosphingolipids | HSO3(-3)GalNAc(b1-4)[HSO3(-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 9780061 | |
| Norovirus | Unknown | Blood group A antigen | Oligosaccharides | Saliva | GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)GlcNAc | Binding | 18701592 |
| Norovirus | Unknown | Blood group A antigen | Oligosaccharides | Saliva | GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)GlcNAc | Not Binding | 18701592 |
| Norovirus | Unknown | Blood group A antigen | Oligosaccharides | Human saliva | GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)GlcNAc | Binding | 16707048 |
| Pseudomonas aeruginosa | PA-IIL | Blood group A antigen | Oligosaccharides | GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)GlcNAc | Binding | 16762477 | |
| Ralstonia solanacearum | RSL (30-kDa proteins) | Blood group A antigen | Oligosaccharides | GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)GlcNAc | Binding | 16762477 | |
| Norovirus | Capsid proteins | Blood group A antigen | Oligosaccharides | GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)GlcNAc | Binding | 18809496 | |
| Helicobacter pylori | BabA (blood group antigen binding adhesin) | Blood group A antigen | Oligosaccharides | GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)GlcNAc | Binding | 15273394 | |
| Streptococcus pneumoniae | FcsSBP (fucose solute-binding protein) | Blood group A antigen | Oligosaccharides | GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)GlcNAc | Binding | 19285508 | |
| Norovirus | Unknown | Blood group A antigen | Oligosaccharides | GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)GlcNAc | Binding | 18599458 | |
| Norovirus | Unknown | Blood group A antigen (A-tri-HSA) | Glycoproteins | Human serum albumin | GalNAc(a1-3)[Fuc(a1-2)]Gal(b)-O-APE | Binding | 19054801 |
| Norovirus | Unknown | Blood group A antigen (A-tri-HSA) | Glycoproteins | Saliva | GalNAc(a1-3)[Fuc(a1-2)]Gal(b)-O-APE | Binding | 18701592 |
| Norovirus | Unknown | Blood group A antigen (A-tri-HSA) | Glycoproteins | GalNAc(a1-3)[Fuc(a1-2)]Gal(b)-O-APE | Binding | 18701592 | |
| Norovirus | Unknown | Blood group A antigen (A-tri-HSA) | Glycoproteins | GalNAc(a1-3)[Fuc(a1-2)]Gal(b)-O-APE | Not Binding | 18701592 | |
| Escherichia coli | hLT | Blood group A antigen analog | Oligosaccharides | Binding | 18809496 | ||
| Helicobacter pylori | BabA (blood group antigen binding adhesin) | Blood group A-Lewis b (ALeb) antigen | Oligosaccharides | GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)[Fuc(a1-4)]GlcNAc | Binding | 15273394 | |
| Norovirus | Unknown | Blood group B antigen | Oligosaccharides | Saliva | Gal(a1-3)[Fuc(a1-2)]Gal | Binding | 18701592 |
