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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source ▲ | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Neisseria gonorrhoeae | Lectin-like proteins (adhesin) | Lewis x (Lex) (GSL) | Oligoglycosylceramides | Gonorrhoeae patients | Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2468365 |
| Neisseria gonorrhoeae | Lectin-like proteins (adhesin) | Lactosylceramide (Lactocerebroside) | Diosylceramides | Gonorrhoeae patients | Gal(b1-4)Glc(b1-1)Cer | Binding | 2468365 |
| Neisseria gonorrhoeae | Lectin-like proteins (adhesin) | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Gonorrhoeae patients | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 2468365 |
| Neisseria gonorrhoeae | Lectin-like proteins (adhesin) | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Gonorrhoeae patients | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2468365 |
| Influenza virus | Unknown | GM3(NeuAc) | Monosialoglycosphingolipids | Granulocytes | NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 8823909 |
| Influenza virus | Unknown | Sialyl-3-Paragloboside (S-3-PG; α2,3-sialylparagloboside) | Monosialoglycosphingolipids | Granulocytes | NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 8823909 |
| Sendai virus | Unknown | Sialyl-3-Paragloboside (S-3-PG; α2,3-sialylparagloboside) | Monosialoglycosphingolipids | Granulocytes | NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 8823909 |
| Influenza virus | Unknown | Sialyl-6-Paragloboside (S-6-PG; α2,6-sialylparagloboside) | Monosialoglycosphingolipids | Granulocytes | NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 8823909 |
| Influenza virus | Unknown | NeuAc3-nLc6Cer (Sialyl neolactohexaosylceramide) | Sialoglycosphingolipids | Granulocytes | NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 8823909 |
| Sendai virus | Unknown | NeuAc3-nLc6Cer (Sialyl neolactohexaosylceramide) | Sialoglycosphingolipids | Granulocytes | NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 8823909 |
| Helicobacter pylori | 35S-labeled or 125I-labeled proteins | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Guinea pig erythrocytes | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 9499377 |
| Lactobacillus johnsonii | Unknown | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Guinea pig erythrocytes | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 11087711 |
| Helicobacter pylori | 35S-labeled or 125I-labeled proteins | GgO3 (de-N- acylated) | Oligoglycosylceramides | Guinea pig erythrocytes | GalNH2(b1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9499377 |
| Escherichia coli | F1C | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Guinea pig erythrocytes | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11877427 |
| Influenza virus | Unknown | Glycoproteins | Glycoproteins | Guinea pig serum | Not Binding | 1740131 | |
| Escherichia coli | 18-kDa fimbrial adhesin | Galactose derivatives | Saccharides | HEp-2 cells | Gal | Binding | 11368522 |
| Campylobacter upsaliensis | 5 bacterial surface proteins (50 to 90-kDa) | Phosphatidylethanolamine (PE) | Non-glycosylated Lipids | HEp-2 cells | Binding | 8926069 | |
| Campylobacter upsaliensis | Unknown | Lyso-PE | Non-glycosylated Lipids | HEp-2 cells | Binding | 8926069 | |
| Shigella dysenteriae | Adhesins | Lipid extracts of Hep-2 cells | Non-glycosylated Lipids | HEp-2 cells | Binding | 11381327 | |
| Actinomyces naeslundii | Adhesins | Asialofetuin | Glycoproteins | HL-60 promyelocytic leukemia cell line | Binding | 11035744 | |
| Streptococcus gordonii | Adhesins | Fetuin | Glycoproteins | HL-60 promyelocytic leukemia cell line | Binding | 11035744 | |
| Actinomyces naeslundii | Adhesins | N-Acetylgalactosamine | Monosaccharides | HL-60 promyelocytic leukemia cell line, Leukosialin (CD43) | GalNAc | Binding | 11035744 |
| Actinomyces naeslundii | Adhesins | Galactose | Monosaccharides | HL-60 promyelocytic leukemia cell line, Leukosialin (CD43) | Gal | Binding | 11035744 |
| Streptococcus gordonii | Adhesins | Sialic acid | Monosaccharides | HL-60 promyelocytic leukemia cell line, Leukosialin (CD43) | Binding | 11035744 | |
| Chlamydia trachomatis | Unknown | N-acetyl-b-maltoheptaosylamine sulfate (SM) | Oligosaccharides | HeLa cells | Binding | 9420059 |
