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RAF/MAP kinase cascade

Summary
Species
Drosophila melanogaster
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
p-T,Y MAPKsp-ERK dimerp21 RAS:GTPp21 RAS:GDPGTPGDPp21 RAS:GTP:PI3KPI3KS-Farn-Me-2xPalmS HRAS:GTPS-Farn-Me_2xPalmS HRAS:GTP:RAL GDS proteinsRglp-T,Y MAPK monomers and dimersp-T,Y MAPK monomers and dimers
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
Displaying all 6 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
P04412 Epidermal growth factor receptor
  • DER
  • Egfr
  • c-erbB
  • top
 view
P16621 Tyrosine-protein phosphatase Lar
  • Lar
 view
Q07407 Fibroblast growth factor receptor homolog 1
  • FR1
  • Tk1
  • htl
 view
Q09147 Fibroblast growth factor receptor homolog 2
  • FR2
  • HD-311
  • Tk2
  • btl
 view
Q94918 Protein vein
  • ddd
  • vn
 view
Q95RU0 Protein cueball
  • cue
 view
If you want to check the location of a particular molecule, you can do so by clicking on the "Switching Highlight" button on the page you have navigated to by clicking on "view".
a simple tooltip
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025