Formation of WDR5-containing histone-modifying complexes

Summary
Species
Drosophila melanogaster
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
Rbbp5RBBP5:ASH2LASH2LKMT2AKMT2A dimerKMT2A dimerMLL1 complexWRAD complexMLL2 complexKMT2B dimerHomologues of KMT2CMLL3 complexMLL4 complextrrSET1A complexSETD1ASETD1BSET1B complexMLL1 complex:MEN1Mnn1HcfMLL1 complex,MLL1 complex:MEN1:HCFC1,HCFC2MLL1 complex,MLL1 complex:MEN1MLL1 complex:MEN1:PSIP1PSIP1MLL2 complex:MEN1MLL2 complex:MEN1:PSIP1CXXC1SET1A complex:WDR82:CXXC1Wdr82SET1A complex:WDR82:CXXC1:HCFC1BOD1BOD1L1:SET1A complex:WDR82:CXXC1SET1B complex:WDR82:CXXC1sxcNSLRcd5wdsdgt1KAT8PHF20nsl1Rcd1
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying all 3 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
P20659 Histone-lysine N-methyltransferase trithorax
  • KMT2A
  • trx
view
Q9V4C8 Host cell factor
  • Hcf
view
Q9VZJ3 GH01794p
  • Dmel\CG1135
  • MCRS1
  • MCRS2
  • Rcd5
  • dMCRS1
  • dMCRS2
  • l(3)r0166
  • l(3)rG166
  • p78
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025