Formation of WDR5-containing histone-modifying complexes

Summary
Species
Drosophila melanogaster
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
ASH2LRBBP5:ASH2LRbbp5KMT2A dimerKMT2A dimerWRAD complexMLL1 complexKMT2B dimerMLL2 complexMLL4 complextrrSET1A complexSETD1ASET1B complexSETD1BMLL1 complex,MLL1 complex:MEN1MLL1 complex,MLL1 complex:MEN1:HCFC1,HCFC2HcfMnn1MLL2 complex:MEN1Wdr82SET1A complex:WDR82:CXXC1CXXC1SET1A complex:WDR82:CXXC1:HCFC1BOD1BOD1L1:SET1A complex:WDR82:CXXC1PHF20NSLnsl1Rcd1sxcKAT8wdsdgt1Rcd5KMT2AHomologues of KMT2CMLL3 complexMLL1 complex:MEN1MLL1 complex:MEN1:PSIP1PSIP1MLL2 complex:MEN1:PSIP1SET1B complex:WDR82:CXXC1
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying all 3 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
P20659 Histone-lysine N-methyltransferase trithorax
  • KMT2A
  • trx
view
Q9V4C8 Host cell factor
  • Hcf
view
Q9VZJ3 GH01794p
  • Dmel\CG1135
  • MCRS1
  • MCRS2
  • Rcd5
  • dMCRS1
  • dMCRS2
  • l(3)r0166
  • l(3)rG166
  • p78
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 4, 2025