Sphingolipid de novo biosynthesis

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
FA2-OH FAH+H2OCYB5B:Fe2+CYB5B:Fe3+O23-ketosphingoidCO2acyl-CoASerCoA-SHsphingoidTPNTPNHDHCE(4E)-CERAphytoceramideCERT1-2COL4A3BPATPADPCOL4A3BPp-S,S132,T-CERT1-2:PPM1L:VAPA/B trimerPPM1L:VAPA/B dimerPiCERT1-2:PPM1L:VAPA/B trimerCERAceramide:CERT1-2:PPM1L:VAPA/B trimerceramide:CERT1-2CERADAGPCSPHMCERADAGPCSPHMC16DH CERDAGPECPESPGS1PSPHK2SPHK2:SPHK2 inhibitorsSPHK2 inhibitorsS1PS1PS1P
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025