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MIRAGE
Ligand-independent caspase activation via DCC

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
DAPKsUnc5B with death domain:DAPKUNC5B(413-945)UNC5AUNC5A(26-340)UNC5A(341-842)UNC5A:NRAGENRAGEDCCDCC(26-1290)DCC(1291-1447)APPL1DCC:DIP13alphaDCC:DIP13alpha:Caspase-9Cleaved Caspase-9CASP3(1-277) dimerADPATPCaspase-3UNC5BUNC5B(27-412)
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
Displaying all 6 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
P43146 Netrin receptor DCC
  • DCC
  • IGDCC1
 view
P55211 Caspase-9
  • CASP9
  • MCH6
 view
Q6ZN44 Netrin receptor UNC5A
  • KIAA1976
  • UNC5A
  • UNC5H1
 view
Q8IZJ1 Netrin receptor UNC5B
  • P53RDL1
  • UNC5B
  • UNC5H2
 view
Q9UKG1 DCC-interacting protein 13-alpha
  • APPL
  • APPL1
  • DIP13A
  • KIAA1428
 view
Q9Y5V3 Melanoma-associated antigen D1
  • MAGED1
  • NRAGE
 view
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025