Antimicrobial peptides

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
CAMP(31-170)LL-37CAMP(134-170):microbial cell surfaceMicrobial cell surfaceDCDYDP-42AIDDDCD1DCD peptidesDCD:anionic phospholipidAnionic phospholipids:microbial cell surfaceZn2+DCD hexamer:Zn(2+):anionic phospholipidsDCD(63-110):anionic phospholipidPGNPGLYRP1dimer:peptidoglycanPGLYRP1 dimerPGLYRP2:peptidoglycanPGLYRP2 dimerH2OL-Ala-gamma-D-Glu-L-Lys-D-Ala(GlcNAc+MurNac)nPGLYRP3,4 dimer:peptidoglycanPGLYRP3,4 dimersREG3A,G propeptideREG3A,G(27-37)REG3A,G(38-175)REG3 proteins:PGNHIPREG3A(38-175):anionic phospholipidsREG3A pore complexITLN1 trimer:Ca2+INTL1:bacterial glycanINTL1 ligandsLPS, PGNRNASEs 3,6,7,(8):LPS,PGNRNases 3,6,7,8RNASEs 3,6,7,(8):anionic phospholipidsGNLY:bacterial anionic lipidsGNLYGNLYGNLY:bacterial anionic lipidsHTN1,3,5:bacterial phospholipidsHTN1,3,5SSA1,SSA2HTN5, (HTN1, HTN3):SSA1,SSA2HTN1,3,5BPIBPI:LPSLPScatestatin:bacterila surfaceCHGA fragmentsPI3PI3:LPSBPIFA/BPIFB:bacterial cellBPIFA/BPIFBLEAP2LEAP2:bacterial phospholipidsEPC:bacterial surfaceEPCLYZLYZ:PGNbetaGlcNAcMurNAc:PeptideELANE,CTSG, PRTN3:microbial cell surfaceHNE, CG, PR3PLA2G2A:Ca2+PLA2G2A:phospholipids
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying entries 1 - 10 of 25 in total
UniProt ID Protein Name Gene Symbol Pathway Viewer
O75594 Peptidoglycan recognition protein 1
  • PGLYRP
  • PGLYRP1
  • PGRP
  • TNFSF3L
view
P02788 Lactotransferrin
  • GIG12
  • LF
  • LTF
view
P07478 Trypsin-2
  • PRSS2
  • TRY2
  • TRYP2
view
P08246 Neutrophil elastase
  • ELA2
  • ELANE
view
P08311 Cathepsin G
  • CTSG
view
P10645 Chromogranin-A
  • CHGA
view
P10909 Clusterin
  • APOJ
  • CLI
  • CLU
  • KUB1
view
P12724 Eosinophil cationic protein
  • ECP
  • RNASE3
  • RNS3
view
P14555 Phospholipase A2, membrane associated
  • PLA2B
  • PLA2G2A
  • PLA2L
  • RASF-A
view
P17213 Bactericidal permeability-increasing protein
  • BPI
view
Displaying all 3 entries
GlyCosmos Lectin UniProt ID Lectin Name Pathway Viewer
GL_001068 Q06141 Regenerating islet-derived protein 3-alpha view
GL_002022 Q8WWA0 Intelectin-1 view
GL_002066 Q6UW15 Regenerating islet-derived protein 3-gamma view
Displaying 1 entry
GlyTouCan ID KEGG GLYCAN ChEBI Pathway Viewer
G49108TO
view
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025