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MIRAGE
MET activates PI3K/AKT signaling

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
GAB1HGF:p-4Y-MET dimer:GAB1HGF:p-4Y-MET dimerHGF:p-4Y-MET dimer:GRB2-1:GAB1Ash-LHGF:p-4Y-MET dimer:GAB1,HGF:p-4Y-MET dimer:GRB2:GAB1ADPATPHGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:PI3KPIK3CA:PIK3R1PIP2PIP3
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
Displaying all 3 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
P08581 Hepatocyte growth factor receptor
  • MET
 view
P14210 Hepatocyte growth factor
  • HGF
  • HPTA
 view
Q13480 GRB2-associated-binding protein 1
  • GAB1
 view
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025