Cargo recognition for clathrin-mediated endocytosis

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
AP-2 ComplexAP-2:cargoAP-2 cargoLDL:LDLR complexDAB2,LDLRAP1:LDLR:LDLDAB2,LDLRAP1DAB2LRP2:DAB2LRP2ubiquitinated cargoEPS15,EPN1,EPN2:ubiquitinated cargoEPS15,EPN1,EPN2UNQLNs:UIM proteinsUBQLN2,1ATPp-AVPR2:AVP(20-28)ADPAVPR2:AVP(20-28)ARRBARRB:ARRB-binding GPCRsARRB-binding GPCRsPI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1ARBBs:ARBB-binding GPCRs:clathrin-coated pitAGFG1AGFG1:VAMP7VAMP7SYT dimersSTON2,1:SYT dimersSTON2,1NEDD8(1-81)NEDD8-STONsNEDD8-STONs:TOR1 hexamer:COP9COP9TOR1 hexamerPICALMsPICALM:VAMP2,3,8VAMP2,3,8AP2:chlorpromazinechlorpromazine
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying all 2 entries
GlyCosmos Lectin UniProt ID Lectin Name Pathway Viewer
GL_002343 P11717 Cation-independent mannose-6-phosphate receptor view
GL_002467 Q9NY64 Solute carrier family 2, facilitated glucose transporter member 8 view
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025