TFAP2 (AP-2) family regulates transcription of growth factors and their receptors

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
AP-2 alpha, gammaTFAP2A,TFAP2C homodimers:ESR1 GeneESR1 GeneESR1ATAD2ATAD2:ESR1CGA GeneCGACGB3 GeneTFAP2A,TFAP2C homodimers:CGB geneCGB3TFAP2A,(TFAP2B,TFAP2C) homo- and heterodimersTFAP2A,(TFAP2B,TFAP2C) homo- and heterodimers:YY1:ERBB2 geneHER2 GeneYY1ERBB2TFAP2A,(TFAP2B) homodimersTFAP2A,(TFAP2B) homodimers:KIT geneKIT GeneVEGFA geneTFAP2A homodimer:VEGFA GeneTFAP2A homodimerVEGFATFAP2A homodimer:TGFA geneTGFA GeneTFAP2C homodimerTFAP2C homodimer:EGFR geneEGFR geneEGFRTFAP2A,TFAP2C homodimers:CGA GeneGonadotropinKITTGFA(24-160)
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025