TFAP2 (AP-2) family regulates transcription of growth factors and their receptors

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
ESR1 GeneTFAP2A,TFAP2C homodimers:ESR1 GeneAP-2 alpha, gammaESR1ATAD2:ESR1ATAD2TFAP2A,TFAP2C homodimers:CGA GeneCGA GeneCGATFAP2A,TFAP2C homodimers:CGB geneCGB3 GeneCGB3GonadotropinYY1TFAP2A,(TFAP2B,TFAP2C) homo- and heterodimers:YY1:ERBB2 geneTFAP2A,(TFAP2B,TFAP2C) homo- and heterodimersHER2 GeneERBB2KIT GeneTFAP2A,(TFAP2B) homodimers:KIT geneTFAP2A,(TFAP2B) homodimersKITTFAP2A homodimerTFAP2A homodimer:VEGFA GeneVEGFA geneVEGFATFAP2A homodimer:TGFA geneTGFA GeneTGFA(24-160)TFAP2C homodimerTFAP2C homodimer:EGFR geneEGFR geneEGFR
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 4, 2025