Transcriptional regulation of granulopoiesis

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
LEF1CEBPA gene: LEF1CEBPA geneCEBPA mRNACEBPACEBPA:CDK4CDK4CEBPE gene:CEBPA dimerCEBPE geneGFI1 geneGFI1 gene:CEBPA dimerCSF3R geneCSF3R gene:SPI1:CEPBA dimer:DEKSPI1DEKIL6R geneIL6RCEBPB mRNALAPMYC gene:CEBPA:E2F1:(TFDP1,TFDP2)MYC gene:E2F1:(TFDP1,TFDP2)MYC geneMYCKLF5 geneKLF5CEBPA gene:RUNX1:SPI1:GATA2:TAL1:FLI1:MYBSCLGATA2AML1FLI1MYBCEBPA:CDK2CDK2p21CEBPA:CDKN1Ap300CEBPE gene:EP300:SPI1:PMLPML_HUMANCEBPE gene:RARA:RXRACEBPE gene:RXRA:RARA:atRAatRACEBPEGFI1CSF3R2x(p-Y705-STAT3)CEBPB gene:p-Y705-STAT3 dimerCEBPB geneCEBPB gene:p-S133-CREB1 dimerphospho-CREB dimerE2F1:(TFDP1,TFDP2)MYC gene:phospho-STAT3:CEBPBKLF5 gene:CEBPA dimerSPI1 gene:Nucleosome
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying entries 1 - 10 of 34 in total
UniProt ID Protein Name Gene Symbol Pathway Viewer
O60814 Histone H2B type 1-K
  • H2BC12
  • H2BFT
  • HIRIP1
  • HIST1H2BK
view
P01106 Myc proto-oncogene protein
  • BHLHE39
  • MYC
view
P04908 Histone H2A type 1-B/E
  • H2AC4
  • H2AC8
  • H2AFA
  • H2AFM
  • HIST1H2AB
  • HIST1H2AE
view
P06899 Histone H2B type 1-J
  • H2BC11
  • H2BFR
  • HIST1H2BJ
view
P08887 Interleukin-6 receptor subunit alpha
  • IL6R
view
P16104 Histone H2AX
  • H2AFX
  • H2AX
view
P17676 CCAAT/enhancer-binding protein beta
  • CEBPB
  • TCF5
view
P23527 Histone H2B type 1-O
  • H2BC17
  • H2BFH
  • H2BFN
  • HIST1H2BO
view
P23769 Endothelial transcription factor GATA-2
  • GATA2
view
P33778 Histone H2B type 1-B
  • H2BC3
  • H2BFF
  • HIST1H2BB
view
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 9, 2024