EGR2 and SOX10-mediated initiation of Schwann cell myelination

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
POU3F1 genePOU3F1 gene:SOX10 dimer:HDAC2:SMARCA4SOX10BRG1HDAC2POU3F1POU3F2EGR2 gene:POU3F1:POU3F2:SOX10EGR2 geneEGR2ADGRG6ADGRG6-CTF:ADGRG6-NTFADGRG6-CTF:ADGRG6-NTFMAG geneMAG gene:EGR2:SOX10MAGMBP gene:EGR2:SOX10MBP geneMBPMPZ gene:EGR2:SOX10:SMARCA4MPZ geneMPZPMP22 GenePMP22 gene:EGR2:SOX10:TEAD1:WWTR1,YAP1TEAD1:WWTR1,YAP1PMP22GJB1 geneGJB11 gene:SOX10:EGR2:NAB1,2NAB1,2PRX genePRX gene:EGR2:SOX10PRXDRP2L-PRX dimer:DRP2L-PRXDystroglycanL-PRX dimer:DRP2:Dystroglycan:Laminin-211MerosinL-PRX:DRP2:dystroglycan:laminin-211:UTRNUTRNHMGCR gene:EGR2:SREBF2 dimerSREBF2 dimerHMGCR geneHMGCRSCD5 gene:EGR2:SREBF2 dimerSCD5 geneSCD5CYP51A1 geneCYP51A1 gene:EGR2:SREBF2 dimerCYP51A1
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying all 2 entries
GlyCosmos Lectin UniProt ID Lectin Name Pathway Viewer
GL_000779 P20916 Myelin-associated glycoprotein view
GL_002357 P25189 Myelin protein P0 view
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 4, 2025