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MIRAGE
Signaling downstream of RAS mutants

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
RAS mutants:GTPRAS mutants:GTP:RAFinactive RAF1,BRAFRAS mutants:GTP:RAF homo/heterodimerADPATPRAS mutants:GTP:p-RAF homo/heterodimerRAF/MAPK scaffoldsmutant RAS:GTP:p-RAF:MAP2Ks:MAPKs:scaffold proteinsMAP2K homo/heterodimersMAPKsmutant RAS:GTP:p-RAF:p-2S MAP2Ks:MAPKs:scaffold proteinsmutant RAS:GTP:p-RAF:p-2S MAP2Ks:p-T,Y MAPKs:scaffold proteinsp-T,Y MAPKsp-2S MAP2K homo/heterodimers
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
Displaying entries 1 - 10 of 28 in total
UniProt ID Protein Name Gene Symbol Pathway Viewer
P01111 GTPase NRas
  • HRAS1
  • NRAS
 view
P01112 GTPase HRas
  • HRAS
  • HRAS1
 view
P01116 GTPase KRas
  • KRAS
  • KRAS2
  • RASK2
 view
P02671 Fibrinogen alpha chain
  • FGA
 view
P02675 Fibrinogen beta chain
  • FGB
 view
P02679 Fibrinogen gamma chain
  • FGG
 view
P02751 Fibronectin
  • FN
  • FN1
 view
P04049 RAF proto-oncogene serine/threonine-protein kinase
  • RAF
  • RAF1
 view
P04275 von Willebrand factor
  • F8VWF
  • VWF
 view
P05106 Integrin beta-3
  • GP3A
  • ITGB3
 view
If you want to check the location of a particular molecule, you can do so by clicking on the "Switching Highlight" button on the page you have navigated to by clicking on "view".
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025