Interleukin-7 signaling

Summary
Species
Mus musculus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
AcK(9,14,18,79)-p(S10,T11)-histone H3BRWD1:AcK(9,14,18,79)-p(S10,T11)-histone H3Brwd1JAK3JAK3:JAK3 inhibitorsJAK3 inhibitorsIL7:IL7R:JAK1IL7:IL7R:JAK1:IL2RG:JAK3IL2RG:JAK3ATPIL7:IL7R:JAK1:IL2RG:p-JAK3ADPIL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:STAT5A,STAT5BSTAT5IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:p-STAT5A,p-STAT5Bp-STAT5IL7:p-Y449-IL7R:JAK1:p-FYN:IL2RG:JAK3:PI3K-regulatory subunitsIL7:p-Y449-IL7R:JAK1:IL2RG:JAK3:PI3K-regulatory subunits:IRS1,IRS2IRS1,2Q3TKT4BRWD1:SMARCA4Il2rgIL7R:JAK1Il7IL7R:TSLP:CRLF2:p-STAT3IL7R:TSLP:CRLF2:STAT3
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: February 17, 2025