NRIF signals cell death from the nucleus

Summary
Species
Mus musculus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
TRAF6 homotrimerNGF ligand:p75NTR:NRIF:TRAF6NGF ligand:p75NTR:NRIFQ9CQ82mature NGF homodimer:p75NTRK63 linked polyubiquitin chainUbiquitinated NRIFUbiquitinated NRIF:SequestosomeSQSTM1Ubiquitinated NRIF:Sequestosome
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying all 5 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
P01139 Beta-nerve growth factor
  • Ngf
  • Ngfb
view
P0CG49 Polyubiquitin-B
  • Ubb
view
P57716 Nicastrin
  • Ncstn
view
Q64337 Sequestosome-1
  • A170
  • STAP
  • Sqstm1
view
Q9Z0W1 Tumor necrosis factor receptor superfamily member 16
  • Ngfr
  • Tnfrsf16
view
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: February 17, 2025