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MIRAGE
Senescence-Associated Secretory Phenotype (SASP)

Summary
Species
Mus musculus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
ATPPhospho-Ribosomal protein S6 kinaseRibosomal protein S6 kinaseADPCDK4,CDK6CDK4,CDK6:INK4Cdkn2bCdh1:phospho-APC/C complexCyclin A:phospho-Cdk(Thr 160):Cdh1:phosho-APC/C complexCCNA:p-T160-CDK2Cyclin A:phospho-Cdk2(Thr 160):phospho-Cdh1:phospho-APC/C complexEHMT1:EHMT2:Cdh1:p-APC/CEHMT1:EHMT2UbUb-EHMT1:Ub-EHMT2:Cdh1:p-APC/CCebpbP28033P28033p-T235,S321-CEBPB homodimer
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
Displaying all 6 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
P0CG49 Polyubiquitin-B
  • Ubb
 view
P18653 Ribosomal protein S6 kinase alpha-1
  • Mapkapk1a
  • Rps6ka1
  • Rsk1
 view
P28033 CCAAT/enhancer-binding protein beta
  • Cebpb
 view
Q5DW34 Histone-lysine N-methyltransferase EHMT1
  • Ehmt1
  • Euhmtase1
  • Glp
  • Kmt1d
 view
Q9CPV2 Anaphase-promoting complex subunit 16
  • Anapc16
  • D10Ertd641e
 view
Q9WVM3 Anaphase-promoting complex subunit 7
  • Anapc7
  • Apc7
 view
If you want to check the location of a particular molecule, you can do so by clicking on the "Switching Highlight" button on the page you have navigated to by clicking on "view".
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025