PKMTs methylate histone lysines

Summary
Species
Mus musculus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
SAMMeK5-histone H3Histone H3SAHMe2K5-histone H3Me3K5-histone H3MeK10-histone H3Me2K10-histone H3Histone H3MeK10-histone H3SAHSAMMe3K10-histone H3MeK28-histone H3Me2K28-histone H3Me3K28-histone H3MeK37-histone H3Me2K37-histone H3Me3K37-histone H3Atf7ipATF7IP:SETDB1SETDB1MeK80-histone H3Me2K80-histone H3Me3K80-histone H3Hist1h4aH4c11H4c11H4c11NFKB1(1-433), NFKB2(1-454):RELANFkB Complex with MeK310-RELA
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying entries 1 - 10 of 19 in total
UniProt ID Protein Name Gene Symbol Pathway Viewer
E9PYH6 Histone-lysine N-methyltransferase SETD1A
  • Setd1a
view
E9Q5F9 Histone-lysine N-methyltransferase SETD2
  • Kiaa1732
  • Kmt3a
  • Setd2
view
O08550 Histone-lysine N-methyltransferase 2B
  • Kmt2b
  • Mll2
  • Trx2
  • Wbp7
view
O88491 Histone-lysine N-methyltransferase, H3 lysine-36 specific
  • Nsd1
view
O88974 Histone-lysine N-methyltransferase SETDB1
  • Eset
  • Kiaa0067
  • Setdb1
view
P25799 Nuclear factor NF-kappa-B p105 subunit
  • Nfkb1
view
P55200 Histone-lysine N-methyltransferase 2A
  • All1
  • Hrx
  • Kmt2a
  • Mll
  • Mll1
view
P62806 Histone H4
  • H4-12
  • H4-53
  • H4c1
  • H4c11
  • H4c12
  • H4c14
  • H4c16
  • H4c2
  • H4c3
  • H4c4
  • H4c6
  • H4c8
  • H4c9
  • H4f16
  • Hist1h4a
  • Hist1h4b
  • Hist1h4c
  • Hist1h4d
  • Hist1h4f
  • Hist1h4h
  • Hist1h4i
  • Hist1h4j
  • Hist1h4k
  • Hist1h4m
  • Hist2h4
  • Hist2h4a
  • Hist4h4
view
Q04207 Transcription factor p65
  • Nfkb3
  • Rela
view
Q5DW34 Histone-lysine N-methyltransferase EHMT1
  • Ehmt1
  • Euhmtase1
  • Glp
  • Kmt1d
view
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025