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MIRAGE
HDR through MMEJ (alt-NHEJ)

Summary
Species
Mus musculus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
RBBP8 homotetramerDNA DSB:MRN:RBBP8DNA DSBs:MRNdNTPH2OMicrohomologous 3'-ssDNA overhangs-DSB:MRN:RBBP8Annealed microhomologous 3'-ssDNA overhangs-DSB:MRN:RBBP8:PARP1,PARP2:FEN1:POLQPARP1,PARP2 dimersPOLQ homodimerFEN1PPiExtended microhomologous 3'-ssDNA overhangs-flap-DSB:MRN:RBBP8:PARP1,PARP2:FEN1:POLQNADExtended microhomologous 3'-ssDNA overhangs-flap-DSB:MRN:RBBP8:FEN1NAMPAR-PARP1,PAR-PARP2 dimersExtended microhomologous 3'-ssDNA overhangs-DSB:MRN:RBBP8FlapExtended microhomologous 3'-ssDNA overhangs-DSB:MRN:RBBP8:LIG3:XRCC1LIG3:XRCC1dsDNA with base substitutions and inter-MMEJ deletionMRN
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
Displaying all 3 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
P11103 Poly [ADP-ribose] polymerase 1
  • Adprp
  • Adprt
  • Adprt1
  • Parp1
 view
P97386 DNA ligase 3
  • Lig3
 view
Q80YR6 DNA endonuclease RBBP8
  • Ctip
  • Rbbp8
 view
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 4, 2025