PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases

Summary
Species
Mus musculus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
p-Y342-Brkp-Y342-PTK6:PXNPxnATPADPQ8VI36p-Y31,Y118-PXN:CRK:DOCK180:ELMO1,ELMO2CRK:DOCK180:ELMO1,ELMO2Rac1:GDPGDPGTPRac1-GTPp-Y342-PTK6:ARHGAP35Q91YM2Q91YM2RhoA:GTPp-Y1105-ARHGAP35:RHOA:GTPRHOA:GDPPiRasa1p-Y1105-ARHGAP35:RASA1p21 RAS:GTP:RASA1p21 RAS:GTPp21 RAS:GDPBcar1p-Y342-PTK6:BCAR1Q61140
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying all 4 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
P32883 GTPase KRas
  • Kras
  • Kras2
view
Q8BPU7 Engulfment and cell motility protein 1
  • Elmo1
view
Q8VI36 Paxillin
  • Pxn
view
Q91YM2 Rho GTPase-activating protein 35
  • Arhgap35
  • Grlf1
  • Kiaa1722
  • P190A
  • p190ARHOGAP
view
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025