RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function

Summary
Species
Mus musculus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
PRMT1RUNX1:CBFB:PRMT1RUNX1:CBFBSAHSAMMeR206,MeR210-RUNX1:CBFB:PRMT1H3K4me2-Nucleosome:ITGA2B gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2BH3K4me3-Nucleosome:ITGA2B gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2BSIN3RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1Hdac1PRMT6RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:ITGA2B gene:H3K4me2-NucleosomeRUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:ITGA2B gene:H3K4me2,H3R2me2a-NucleosomeRUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:GP1BA gene:H3K4me2-NucleosomeRUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:GP1BA gene:H3K4me2,H3R2me2a-NucleosomeH3K4me2-Nucleosome:GP1BA gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2BH3K4me3-Nucleosome:GP1BA gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2BH3K4me2-Nucleosome:THBS1 gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2BH3K4me3-Nucleosome:THBS1 gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2BRUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:THBS1 gene:H3K4me2-NucleosomeRUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:THBS1B gene:H3K4me2,H3R2me2a-NucleosomeH3K4me2-Nucleosome:MIR27A gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2BH3K4me3-Nucleosome:MIR27A gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2BRUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:MIR27A gene:H3K4me2-NucleosomeRUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:MIR27A gene:H3K4me2,H3R2me2a-Nucleosome
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying entry 21 - 21 of 21 in total
UniProt ID Protein Name Gene Symbol Pathway Viewer
Q9JHD1 Histone acetyltransferase KAT2B
  • Kat2b
  • Pcaf
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International Collaboration

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025